Functional and biochemical dissection of the structure-specific nuclease ARTEMIS (Q24564574)

1

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Yunmei Ma

2

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Doris Niewolik

4

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Michael R Lieber

5

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Klaus Schwarz

The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination

6

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language of work or name

English

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publication date

5 May 2004

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published in

The EMBO Journal

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volume

23

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page(s)

1987-97

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issue

9

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cites work

1 reference

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Nonhomologous end joining and V(D)J recombination require an additional factor

24 March 2017

1 reference

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Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family

24 March 2017

1 reference

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

24 March 2017

1 reference

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

24 March 2017

1 reference

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The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae

24 March 2017

1 reference

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Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

24 March 2017

1 reference

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

24 March 2017

1 reference

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Mechanistic constraints on diversity in human V(D)J recombination

24 March 2017

1 reference

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

24 March 2017

1 reference

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Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

24 March 2017

1 reference

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Somatic generation of antibody diversity

24 March 2017

1 reference

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V(D)J recombination: RAG proteins, repair factors, and regulation

7 April 2017

1 reference

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An evolutionary classification of the metallo-beta-lactamase fold proteins.

27 September 2017

1 reference

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Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

27 September 2017

1 reference

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Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination

27 September 2017

1 reference

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Metallo-beta-lactamase: structure and mechanism

27 September 2017

1 reference

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The V(D)J recombination activating gene, RAG-1.

27 September 2017

1 reference

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Transformation of mammalian cells with genes from procaryotes and eucaryotes

27 September 2017

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RAG mutations in human B cell-negative SCID.

27 September 2017

1 reference

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The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

27 September 2017

1 reference

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Homologous pairing and DNA strand-exchange proteins.

27 September 2017

1 reference

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Chimerism of Murine Fetal Bone Marrow by Maternal Cells Occurs in Late Gestation and Persists into Adulthood

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15071507