The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam (Q24561949)

23 June 2017

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam (English)

1 reference

23 June 2017

1 reference

Berkley A Lynch

1

Berkley A

Lynch

1 reference

23 June 2017

Nathalie Lambeng

2

Nathalie

Lambeng

1 reference

23 June 2017

Karl Nocka

3

Karl

Nocka

1 reference

23 June 2017

Patricia Kensel-Hammes

4

Patricia

Kensel-Hammes

1 reference

23 June 2017

Sandra M Bajjalieh

5

Sandra M

Bajjalieh

1 reference

23 June 2017

Alain Matagne

6

Alain

Matagne

1 reference

23 June 2017

Bruno Fuks

7

Bruno

Fuks

1 reference

23 June 2017

language of work or name

English

0 references

publication date

21 June 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

23 June 2017

1 reference

23 June 2017

101

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23 June 2017

26

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23 June 2017

9861-9866

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Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

23 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

SV2, a brain synaptic vesicle protein homologous to bacterial transporters

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Moonlighting proteins: old proteins learning new tricks.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Control of neurotransmitter release by an internal gel matrix in synaptic vesicles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Levetiracetam: a novel antiepileptic drug

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The evaluation and treatment of seizures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Differential expression of synaptic vesicle protein 2 (SV2) isoforms.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The synaptic vesicle protein SV2 is a novel type of transmembrane transporter

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Desynchronizing effect of levetiracetam on epileptiform responses in rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Binding characteristics of [3H]ucb 30889 to levetiracetam binding sites in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

SV2 modulates the size of the readily releasable pool of secretory vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Phosphorylation of synaptic vesicle protein 2 modulates binding to synaptotagmin

21 January 2018

1 reference

12 December 2020

Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures

1 reference

12 December 2020

Levetiracetam (ucb LO59) affects in vitro models of epilepsy in CA3 pyramidal neurons without altering normal synaptic transmission

1 reference

12 December 2020

Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0308208101

1 reference

release_cennw5qmjndjnaqvq3b22y3qem

23 June 2017

0 references

0 references

OpenCitations bibliographic resource ID

312837

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference