Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex (Q24561609)

ubiquitin protein ligase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Tohru Kiyono

3

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author name string

Lindy Gewin

1

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Hadley Myers

2

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Denise A Galloway

describes a project that uses

4

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language of work or name

English

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publication date

15 September 2004

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published in

Genes & Development

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volume

18

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page(s)

2269-82

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issue

18

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ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC517520/fullTextXML

inferred from PubMed Central ID database lookup

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27 September 2017

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27 September 2017

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E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc

27 September 2017

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27 September 2017

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Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells

27 September 2017

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The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

1 reference

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Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.

27 September 2017

1 reference

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E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

27 September 2017

1 reference

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Viral oncogenes accelerate conversion to immortality of cultured conditionally immortal human mammary epithelial cells

27 September 2017

1 reference

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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Telomerase maintains telomere structure in normal human cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Inhibition of telomerase limits the growth of human cancer cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=517520

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

28 November 2018

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12 December 2020

Methylation of the human telomerase gene CpG island

1 reference

12 December 2020

Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription

1 reference

12 December 2020

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

1 reference

12 December 2020

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

12 December 2020

Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element

1 reference

12 December 2020

Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.1214704

1 reference

4015653

4015653

1 reference

1 reference

1 reference