A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase (Q24560013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Frederick Berkovitch

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Elham Behshad

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Kuo-Hsiang Tang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Perry A Frey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Catherine L Drennan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

28 October 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

4 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

15870-15875

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme

4 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Radical Shuttling in a Protein: Ribose Pseudorotation Controls Alkyl-Radical Transfer in the Coenzyme B(12) Dependent Enzyme Glutamate Mutase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Automated MAD and MIR structure solution

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Radical catalysis in coenzyme B12-dependent isomerization (eliminating) reactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Radical carbon skeleton rearrangements: catalysis by coenzyme B12-dependent mutases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Enzyme catalysis of 1,2-amino shifts: the cooperative action of B6, B12, and aminomutases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

The manifold of vitamin B6 dependent enzymes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Studies on the fermentation of D-alpha-lysine. Purification and properties of an adenosine triphosphate regulated B 12-coenzyme-dependent D-alpha-lysine mutase complex from Clostridium sticklandii

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Electron spin resonance studies with dioldehydrase. Evidence for radical intermediates in reactions catalyzed by coenzyme B 12.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

The role of S-adenosylmethionine in the lysine 2,3-aminomutase reaction.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Metal cofactors of lysine-2,3-aminomutase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528771

Characterization of the coenzyme-B12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-lysine 5, 6-aminomutase from Clostridium sticklandii

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Identification of a novel pyridoxal 5'-phosphate binding site in adenosylcobalamin-dependent lysine 5,6-aminomutase from Porphyromonas gingivalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Kinetic and biochemical analysis of the mechanism of action of lysine 5,6-aminomutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Tyrosine 89 Accelerates Co−Carbon Bond Homolysis in Methylmalonyl-CoA Mutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

Electron transfer in the substrate-dependent suicide inactivation of lysine 5,6-aminomutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0407074101

XAS spectroscopy reveals X-ray-induced photoreduction of free and protein-bound B12 cofactors

21 January 2018

1 reference

12 December 2020

Identification and cobamide coenzyme-dependent formation of 3,5-diaminohexanoic acid, an intermediate in lysine fermentation

1 reference

12 December 2020

Purification and properties of β-lysine mutase, a pyridoxal phosphate and B12 coenzyme dependent enzyme

1 reference

12 December 2020

Direct spectrophotometric observation of an intermediate formed from deoxyadenosylcobalamin in ribonucleotide reduction

1 reference

12 December 2020

The role of pyridoxal phosphate in the B 12 Coenzyme-dependent D- -lysine mutase reaction

1 reference

12 December 2020

Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme

1 reference

12 December 2020

The role of the B12 coenzyme in the conversion of 1,2-propanediol to propionaldehyde

1 reference

12 December 2020

Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0407074101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15514022%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

15514022

1 reference