GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction (Q24553130)

1

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Jing Ma

2

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Guochang Huang

3

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Tong Zhang

4

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Veronica Novotny-Diermayr

5

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Chin Thing Ong

6

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Xinmin Cao

Endofin, an endosomal FYVE domain protein

7

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language of work or name

English

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publication date

17 March 2003

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published in

The EMBO Journal

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volume

22

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issue

6

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page(s)

1325-35

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cites work

1 reference

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The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6

24 March 2017

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Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach

24 March 2017

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Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

24 March 2017

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Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

24 March 2017

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Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

24 March 2017

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

24 March 2017

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

24 March 2017

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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

24 March 2017

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A new protein containing an SH2 domain that inhibits JAK kinases

24 March 2017

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24 March 2017

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

24 March 2017

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Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

24 March 2017

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Activation and association of Stat3 with Src in v-Src-transformed cell lines

24 March 2017

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A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors

24 March 2017

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EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

24 March 2017

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

24 March 2017

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CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells

24 March 2017

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

24 March 2017

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How cells respond to interferons

24 March 2017

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

24 March 2017

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

24 March 2017

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GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)

24 March 2017

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Negative regulation of cytokine signaling pathways

24 March 2017

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Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

24 March 2017

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Specific inhibition of Stat3 signal transduction by PIAS3

24 March 2017

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Structure and function of a new STAT-induced STAT inhibitor

24 March 2017

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

24 March 2017

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Stat3 and Stat4: members of the family of signal transducers and activators of transcription

24 March 2017

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7 April 2017

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Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

7 April 2017

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

7 April 2017

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

7 April 2017

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Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3.

27 September 2017

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The Stat family in cytokine signaling

27 September 2017

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Roles of STAT3 defined by tissue-specific gene targeting

27 September 2017

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

27 September 2017

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Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

27 September 2017

1 reference

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Thioredoxin reductase mediates cell death effects of the combination of beta interferon and retinoic acid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Stat3 activation is required for cellular transformation by v-src

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

27 September 2017

1 reference

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Vitamin A, differentiation and cancer

27 September 2017

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Jak-STAT signaling induced by the v-abl oncogene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Characterization of monoclonal antibodies against GRIM-19, a novel IFN-beta and retinoic acid-activated regulator of cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

The vesicular stomatitis virus matrix protein inhibits glycoprotein 130-dependent STAT activation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151078

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

28 November 2018

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12 December 2020

Interdomain interaction of Stat3 regulates its Src homology 2 domain-mediated receptor binding activity

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12 December 2020

Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples

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12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG135

1 reference

4855317

4855317

1 reference

1 reference

1 reference