IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro (Q24337245)

7

Moin A Saleem

0 references

Patrick Auguste

Patrick Auguste

2

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Gavin I Welsh

Gavin I Welsh

3

0 references

Christian Combe

Christian Combe

9

0 references

author name string

Claire Rigothier

1

0 references

Sébastien Lepreux

4

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Colette Deminière

5

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Jean Ripoche

Creative Commons Attribution 4.0 International

8

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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page(s)

e37695

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issue

5

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copyright license

start time

25 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin

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IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

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IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

19 March 2017

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Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes

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Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

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Enhanced podocalyxin expression alters the structure of podocyte basal surface

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IQGAP1 binds ERK2 and modulates its activity

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Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

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IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin

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Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

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IQGAP1 and calmodulin modulate E-cadherin function

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

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Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42

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Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

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Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex

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Proteinuria: an enzymatic disease of the podocyte?

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Site-specific expression of IQGAP1, a key mediator of cytoskeleton, in mouse renal tubules

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IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly

27 September 2017

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27 September 2017

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Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact

27 September 2017

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27 September 2017

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CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain

27 September 2017

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27 September 2017

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Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and function

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360763

IQGAP1 mediates VE-cadherin-based cell-cell contacts and VEGF signaling at adherence junctions linked to angiogenesis.

27 September 2017

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037695

IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037695

Endothelial IQGAP1 regulates efficient lymphocyte transendothelial migration

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037695

MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360763

Congenital nephrotic syndrome in mice lacking CD2-associated protein

29 November 2018

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The glomerular slit diaphragm is a modified adherens junction

29 November 2018

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