Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP (Q24336559)

GOA release 2020-03-11

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Madelyn S Hanson

1

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Alan H Stephenson

2

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Elizabeth A Bowles

3

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Meera Sridharan

4

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Shaquria Adderley

5

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Randy S Sprague

American Journal of Physiology Heart and Circulatory Physiology

6

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language of work or name

English

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publication date

August 2008

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published in

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volume

295

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issue

2

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page(s)

H786-93

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cites work

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Integrin-mediated platelet adhesion.

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NO inhibits signal transduction pathway for ATP release from erythrocytes via its action on heterotrimeric G protein Gi.

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Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi.

21 January 2018

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Short-term and long-term effects of one-week treatment with intravenous iloprost in critical limb ischemia patients (Leriche-Fontaine stage III and IV).

29 November 2018

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cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

29 November 2018

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Participation of cAMP in a signal-transduction pathway relating erythrocyte deformation to ATP release

29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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Human erythrocytes contain Ca2+, calmodulin-dependent cyclic nucleotide phosphodiesterase which is involved in the hydrolysis of cGMP.

29 November 2018

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Adenylate cyclase in the maturing human reticulocyte: selective loss of the catalytic unit, but not of the receptor-cyclase coupling protein

29 November 2018

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cAMP-induced changes of intracellular free Mg2+ levels in human erythrocytes

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Beta-adrenergic agonists regulate cell membrane fluctuations of human erythrocytes

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Reduced expression of G(i) in erythrocytes of humans with type 2 diabetes is associated with impairment of both cAMP generation and ATP release

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Ontogeny of catecholamine and adenosine receptor-mediated cAMP signaling of embryonic red blood cells: role of cGMP-inhibited phosphodiesterase 3 and hemoglobin

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Subthreshold doses of specific phosphodiesterase type 3 and 4 inhibitors enhance the pulmonary vasodilatory response to nebulized prostacyclin with improvement in gas exchange

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Stimulation of erythroid cells adenylate cyclase by soluble factors

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Loss of beta-adrenergic receptor-guanine nucleotide regulatory protein interactions accompanies decline in catecholamine responsiveness of adenylate cyclase in maturing rat erythrocytes

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Studies on adenosine 3′,5′-monophosphate phosphodiesterase of human erythrocyte membranes

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Occurrence of adenyl cyclase activity in human erythrocytes

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10.1152/AJPHEART.00349.2008

Identifiers

DOI

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2094084

2094084

1 reference

1 reference

1 reference