Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism (Q24329236)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

0 references

0 references

Unc-51 like autophagy activating kinase 2

1 reference

Unc-51 like autophagy activating kinase 1

1 reference

Autophagy related 13

1 reference

protein autophosphorylation

1 reference

author

Sharon Tooze

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Edmond Y W Chan

1

1 reference

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24 December 2019

Andrea Longatti

2

1 reference

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24 December 2019

Nicole C McKnight

3

1 reference

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24 December 2019

language of work or name

English

0 references

publication date

20 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

24 December 2019

published in

1 reference

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24 December 2019

volume

29

1 reference

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24 December 2019

page(s)

157-171

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24 December 2019

issue

1

1 reference

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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

24 December 2019

cites work

1 reference

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Organization of the pre-autophagosomal structure responsible for autophagosome formation

19 March 2017

1 reference

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siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

19 March 2017

1 reference

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Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

19 March 2017

1 reference

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

19 March 2017

1 reference

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An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase

19 March 2017

1 reference

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Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy

19 March 2017

1 reference

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A Drosophila protein-interaction map centered on cell-cycle regulators

19 March 2017

1 reference

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Role of Unc51.1 and its binding partners in CNS axon outgrowth

19 March 2017

1 reference

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Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy

19 March 2017

1 reference

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Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole

19 March 2017

1 reference

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Tor-mediated induction of autophagy via an Apg1 protein kinase complex

19 March 2017

1 reference

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Autophagy fights disease through cellular self-digestion

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Autophagy in the Pathogenesis of Disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

The role of autophagy during the early neonatal starvation period

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Autophagy genes are essential for dauer development and life-span extension in C. elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

The cell biology of autophagy in metazoans: a developing story

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Function of the Dictyostelium discoideum Atg1 kinase during autophagy and development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Role of mitochondrial permeability transition pores in mitochondrial autophagy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Dual role of Atg1 in regulation of autophagy-specific PAS assembly in Saccharomyces cerevisiae.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

Dictyostelium macroautophagy mutants vary in the severity of their developmental defects.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612494

ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18936157

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01082-08

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18936157%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

2 references