Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49 (Q24324667)

DExD-box helicase 39A

1 reference

DExD-box helicase 39B

1 reference

MX dynamin-like GTPase 1

1 reference

author name string

Christian Wisskirchen

1

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Thomas H Ludersdorfer

2

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Dominik A Müller

3

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Eva Moritz

4

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Jovan Pavlovic

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

7 October 2011

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published in

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volume

286

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issue

40

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page(s)

34743-51

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3186362/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56

19 March 2017

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Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins

19 March 2017

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Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle

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Structural basis of oligomerization in the stalk region of dynamin-like MxA

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Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus

19 March 2017

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Interferon-induced antiviral Mx1 GTPase is associated with components of the SUMO-1 system and promyelocytic leukemia protein nuclear bodies

19 March 2017

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Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

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U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction

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UAP56 is an important regulator of protein synthesis and growth in cardiomyocytes

19 March 2017

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Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

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The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity

7 April 2017

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The cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infection

27 September 2017

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The viral nucleoprotein determines Mx sensitivity of influenza A viruses

27 September 2017

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Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity

27 September 2017

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Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity

27 September 2017

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Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export

27 September 2017

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UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export

27 September 2017

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Assembly and mobility of exon-exon junction complexes in living cells

27 September 2017

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Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase

27 September 2017

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Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches

27 September 2017

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Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum

27 September 2017

1 reference

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Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.

27 September 2017

1 reference

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Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome

27 September 2017

1 reference

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Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

27 September 2017

1 reference

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The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

A monomeric GTPase-negative MxA mutant with antiviral activity

27 September 2017

1 reference

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Nuclear cotransport mechanism of cytoplasmic human MxB protein

27 September 2017

1 reference

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A functional GTP-binding motif is necessary for antiviral activity of Mx proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Overexpression of the influenza virus polymerase can titrate out inhibition by the murine Mx1 protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Nuclear localization of mouse Mx1 protein is necessary for inhibition of influenza virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Mechanism of human MxA protein action: variants with changed antiviral properties

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Function of the mouse Mx1 protein is inhibited by overexpression of the PB2 protein of influenza virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Vesicular stomatitis virus transcription inhibited by purified MxA protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Intramolecular backfolding of the carboxyl-terminal end of MxA protein is a prerequisite for its oligomerization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

GTP-bound human MxA protein interacts with the nucleocapsids of Thogoto virus (Orthomyxoviridae).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362

Domains mediating intramolecular folding and oligomerization of MxA GTPase.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.251843

Binding of ATP to UAP56 is necessary for mRNA export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.251843

UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.251843

Mx1 GTPase accumulates in distinct nuclear domains and inhibits influenza A virus in cells that lack promyelocytic leukaemia protein nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.251843

Induction of the PML protein by interferons in normal and APL cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186362