DJ-1 binds to mitochondrial complex I and maintains its activity (Q24324507)

positive regulation of mitochondrial electron transport, NADH to ubiquinone

GOA release 2020-03-11

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Parkinson disease (autosomal recessive, early onset) 7

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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Takuya Hayashi

1

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Chikako Ishimori

2

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Kazuko Takahashi-Niki

3

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Takahiro Taira

4

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Yun-chul Kim

5

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Hiroshi Maita

6

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Chinatsu Maita

7

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Hiroyoshi Ariga

8

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Sanae M M Iguchi-Ariga

Biochemical and Biophysical Research Communications

9

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language of work or name

English

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publication date

18 December 2009

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published in

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volume

390

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page(s)

667-72

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issue

3

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cites work

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

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Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

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DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

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Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

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Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

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7 January 2021

Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients

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7 January 2021

The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein

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7 January 2021

Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection

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Mitochondrial involvement in Parkinson's disease

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7 January 2021

Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities

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DJ-1 has a role in antioxidative stress to prevent cell death

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Neurochemical and neurogenetic correlates of Parkinson's disease.

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

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DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

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DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor

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7 January 2021

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

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7 January 2021

DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

1 reference

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7 January 2021

Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress

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The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease

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Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).

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Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

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Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1.

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Mitochondrial complex I deficiency in Parkinson's disease

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells

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7 January 2021

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

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7 January 2021

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

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7 January 2021