A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation (Q24324426)

GOA release 2020-03-11

epidermis morphogenesis

1 reference

GOA release 2020-03-11

author

Eleftherios P. Diamandis

8

object named as

Eleftherios P Diamandis

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Iacovos P Michael

object named as

Iacovos P Michael

2

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author name string

Carla A Borgoño

1

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Nahoko Komatsu

3

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Arumugam Jayakumar

4

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Ravi Kapadia

5

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Gary L Clayman

6

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Georgia Sotiropoulou

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

9 February 2007

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published in

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volume

282

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issue

6

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page(s)

3640-52

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cites work

1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

A chymotrypsin-like proteinase that may be involved in desquamation in plantar stratum corneum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

In vivo significance of kinetic constants of protein proteinase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Theoretical and practical aspects of proteinase inhibition kinetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Complex formation between human kallikrein 13 and serum protease inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Recombinant production, purification and biochemical characterization of domain 6 of LEKTI: a temporary Kazal-type-related serine proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Expression of LEKTI domains 6-9' in the baculovirus expression system: recombinant LEKTI domains 6-9' inhibit trypsin and subtilisin A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

LEKTI: a multidomain serine proteinase inhibitor with pathophysiological relevance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Kinetics of the inhibition of human leukocyte elastase by elafin, a 6-kilodalton elastase-specific inhibitor from human skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

https://api.crossref.org/works/10.1074%2FJBC.M607567200

1 reference

7 January 2021

Are desmosomes more than tethers for intermediate filaments?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

SPINK5, the defective gene in netherton syndrome, encodes multiple LEKTI isoforms derived from alternative pre-mRNA processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Evolutionary families of peptidase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Targetting of desmoglein 1 in inherited and acquired skin diseases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Compositionally different desmosomes in the various compartments of the human hair follicle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Protein C inhibitor is expressed in keratinocytes of human skin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Stratum corneum tryptic enzyme in normal epidermis: a missing link in the desquamation process?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

The spectrum of pathogenic mutations in SPINK5 in 19 families with Netherton syndrome: implications for mutation detection and first case of prenatal diagnosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Calcium-dependent conformation of desmoglein 1 is required for its cleavage by exfoliative toxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Complexity and expression patterns of the desmosomal cadherins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Serpin-derived peptide substrates for investigating the substrate specificity of human tissue kallikreins hK1 and hK2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

LEKTI, a novel 15-domain type of human serine proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Roles of the P1, P2, and P3 residues in determining inhibitory specificity of kallistatin toward human tissue kallikrein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

A novel protease inhibitor of the alpha2-macroglobulin family expressed in the human epidermis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Evidence that major 78-44-kD concanavalin A-binding glycopolypeptides in pig epidermis arise from the degradation of desmosomal glycoproteins during terminal differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Antileukoprotease in psoriatic scales

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Cell shedding from human plantar skin in vitro: evidence of its dependence on endogenous proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Identification of Late Differentiation Antigens of Human Cornified Epithelia, Expressed in Re-Organized Desmosomes and Bound to Cross-Linked Envelope

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Evidence that stratum corneum chymotryptic enzyme is transported to the stratum corneum extracellular space via lamellar bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Evidence that Cell Shedding from Plantar Stratum Corneum In Vitro Involves Endogenous Proteolysis of the Desmosomal Protein Desmoglein I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Epidermal lamellar granules transport different cargoes as distinct aggregates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

A proteolytic cascade of kallikreins in the stratum corneum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Quantification of human tissue kallikreins in the stratum corneum: dependence on age and gender

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Netherton syndrome in two Japanese siblings with a novel mutation in the SPINK5 gene: immunohistochemical studies of LEKTI and other epidermal molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Plasminogen activator inhibitor-2 is expressed in different types of congenital ichthyosis: in vivo evidence for its cross-linking into the cornified cell envelope by transglutaminase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Protein inhibitors of proteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Immunolocalization of stratum corneum chymotryptic enzyme in human skin and oral epithelium with monoclonal antibodies: evidence of a proteinase specifically expressed in keratinizing squamous epithelia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Enzymatic profiling of human kallikrein 14 using phage-display substrate technology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607567200

7 January 2021