Characterization of the DNA binding specificity of Shelterin complexes (Q24323345)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0090655

Protection of telomeres 1

1 reference

TERF1 interacting nuclear factor 2

1 reference

telomeric repeat binding factor 1

1 reference

ACD shelterin complex subunit and telomerase recruitment factor

1 reference

Telomeric repeat binding factor 2

1 reference

TERF2 interacting protein

1 reference

author name string

Kyung H Choi

1

0 references

Amy S Farrell

2

0 references

Amanda S Lakamp

3

0 references

Michel M Ouellette

Creative Commons Attribution-NonCommercial 3.0 Unported

4

0 references

language of work or name

English

0 references

publication date

November 2011

0 references

published in

Nucleic Acids Research

0 references

volume

39

0 references

issue

21

0 references

page(s)

9206-23

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copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Telomere protection by mammalian Pot1 requires interaction with Tpp1

19 March 2017

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TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

19 March 2017

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A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

19 March 2017

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POT1 and TRF2 cooperate to maintain telomeric integrity

19 March 2017

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

19 March 2017

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A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2

19 March 2017

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POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

19 March 2017

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PTOP interacts with POT1 and regulates its localization to telomeres

19 March 2017

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POT1 as a terminal transducer of TRF1 telomere length control

19 March 2017

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Control of human telomere length by TRF1 and TRF2

19 March 2017

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TIN2, a new regulator of telomere length in human cells

19 March 2017

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Mammalian telomeres end in a large duplex loop

19 March 2017

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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

19 March 2017

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19 March 2017

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A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins

19 March 2017

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Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2

19 March 2017

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Homologous recombination generates T-loop-sized deletions at human telomeres

19 March 2017

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TRF2 Protects Human Telomeres from End-to-End Fusions

19 March 2017

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Shelterin: the protein complex that shapes and safeguards human telomeres

19 March 2017

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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

19 March 2017

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Loss of hPot1 function leads to telomere instability and a cut-like phenotype

19 March 2017

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Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

19 March 2017

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TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres

19 March 2017

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TIN2 mediates functions of TRF2 at human telomeres

19 March 2017

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DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites

19 March 2017

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Pot1, the putative telomere end-binding protein in fission yeast and humans

19 March 2017

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

19 March 2017

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How shelterin protects mammalian telomeres

19 March 2017

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A DNA damage checkpoint response in telomere-initiated senescence

7 April 2017

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DNA damage foci at dysfunctional telomeres

7 April 2017

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Protection of mammalian telomeres

7 April 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Dynamics of protein binding to telomeres in living cells: implications for telomere structure and function

27 September 2017

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T-loops and the origin of telomeres

27 September 2017

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Cell cycle localization, dimerization, and binding domain architecture of the telomere protein cPot1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

Immortalization with telomerase of the Nestin-positive cells of the human pancreas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

Different telomere damage signaling pathways in human and mouse cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

TRF1 binds a bipartite telomeric site with extreme spatial flexibility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241663

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKR665

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKR665

An agarose-acrylamide composite native gel system suitable for separating ultra-large protein complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21852327

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21852327

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transferrin-facilitated lipofection gene delivery strategy: characterization of the transfection complexes and intracellular trafficking

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21852327

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKR665

1 reference

1 reference

1 reference

PubMed publication ID

21852327

1 reference