Diabetes mutations delineate an atypical POU domain in HNF-1alpha (Q24321858)

protein dimerization activity

GOA release 2020-03-11

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GOA release 2020-03-11

author

Sirano Dhe-Paganon

5

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author name string

Young-In Chi

1

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J Daniel Frantz

2

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Byung-Chul Oh

3

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Lone Hansen

4

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Steven E Shoelson

MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X)

6

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language of work or name

English

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publication date

November 2002

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published in

Molecular Cell

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volume

10

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issue

5

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page(s)

1129-37

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cites work

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Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young

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Mutations in the Hepatocyte Nuclear Factor-1 Gene Are a Common Cause of Maturity-Onset Diabetes of the Young in the U.K

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Novel MODY3 Mutations in the Hepatocyte Nuclear Factor-1 Gene: Evidence for a Hyperexcitability of Pancreatic -cells to Intravenous Secretagogues in a Glucose-Tolerant Carrier of a P447L Mutation

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Maturity-onset diabetes of the young: clinical heterogeneity explained by genetic heterogeneity

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Youth-onset type 2 diabetes (Y2DM) associated with HNF1A S319 in aboriginal Canadians

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Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface

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Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12453420

1 reference

Consolidated OpenCitations Corpus – April 2017