Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells (Q24321135)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

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GOA release 2020-03-11

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V S Budhram-Mahadeo

1

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S Irshad

2

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S Bowen

3

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S A Lee

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L Samady

5

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G P Tonini

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D S Latchman

Cyclin D1 in breast cancer

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language of work or name

English

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publication date

3 January 2008

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published in

Oncogene

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volume

27

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issue

1

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page(s)

145-54

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cites work

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Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

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A novel cyclin encoded by a bcl1-linked candidate oncogene

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Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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The retinoblastoma protein and cell cycle control

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Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors

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Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells

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CDK-independent activation of estrogen receptor by cyclin D1

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Cyclin D1 represses STAT3 activation through a Cdk4-independent mechanism.

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Neuroblastoma: biological insights into a clinical enigma

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The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells

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The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

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Targeting Brn-3b in breast cancer therapy

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The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells

21 January 2018

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Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

21 January 2018

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POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells

21 January 2018

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Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis

21 January 2018

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The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo

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The Brn-3a transcription factor

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Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration

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A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells

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Gene expression in the developing mouse retina by EST sequencing and microarray analysis

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Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element

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Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor

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Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

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Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

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Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit

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The Putative Oncogene PRAD1 Encodes a Novel Cyclin

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The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors

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Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter

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Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma

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Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases

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Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapy

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The functionally antagonistic POU family transcription factors Brn-3a and Brn-3b show opposite changes in expression during the growth arrest and differentiation of human neuroblastoma cells

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