Notum deacylates Wnt proteins to suppress signalling activity (Q24320646)

3

0 references

Tao-hsin Chang

5

Tao-Hsin Chang

0 references

Ambrosius P. Snijders

Ambrosius P Snijders

10

0 references

Nicola O'Reilly

Nicola O'Reilly

9

0 references

Ten Feizi

7

Ten Feizi

0 references

Yvonne Jones

11

E Yvonne Jones

0 references

author name string

Satoshi Kakugawa

1

0 references

Paul F Langton

2

0 references

Steven A Howell

4

0 references

Yan Liu

6

0 references

Ganka Bineva

8

0 references

Jean-Paul Vincent

describes a project that uses

12

0 references

language of work or name

English

0 references

publication date

12 March 2015

0 references

published in

Nature

0 references

volume

519

0 references

issue

7542

0 references

page(s)

187-92

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4376489/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion

19 March 2017

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Alpha/beta hydrolase fold enzymes: the family keeps growing

19 March 2017

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A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS)

19 March 2017

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Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein

19 March 2017

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The neoglycolipid (NGL)-based oligosaccharide microarray system poised to decipher the meta-glycome

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Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract

19 March 2017

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HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient

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Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/Armadillo

7 April 2017

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The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

27 September 2017

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Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway

27 September 2017

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27 September 2017

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Steep differences in wingless signaling trigger Myc-independent competitive cell interactions

27 September 2017

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Refined LexA transactivators and their use in combination with the Drosophila Gal4 system

27 September 2017

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Shaping morphogen gradients by proteoglycans

27 September 2017

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A study on the interactions between heparan sulfate proteoglycans and Wnt proteins.

27 September 2017

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Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.

27 September 2017

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A critical role for endocytosis in Wnt signaling

27 September 2017

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Heparan sulphate proteoglycans: the sweet side of development

27 September 2017

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Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions

27 September 2017

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Wingful, an extracellular feedback inhibitor of Wingless

27 September 2017

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Feedback control of intercellular signalling in development

27 September 2017

1 reference

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Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila

27 September 2017

1 reference

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Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Covalent lipid modifications of proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Sulfated is a negative feedback regulator of wingless in Drosophila

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

The endocytic pathway and formation of the Wingless morphogen gradient

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Dpp gradient formation in the Drosophila wing imaginal disc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Spatial regulation of Wingless morphogen distribution and signaling by Dally-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Expression of mung bean pectin acetyl esterase in potato tubers: effect on acetylation of cell wall polymers and tuber mechanical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Patterning and growth control by membrane-tethered Wingless.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14259

Detection of glycophospholipid anchors on proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4376489

29 November 2018

Identifiers

DOI

10.1038/NATURE14259

1 reference

Dimensions Publication ID

612375

1049644865

0 references

612375

1 reference

1 reference

1 reference