Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network (Q24320381)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

24 February 2020

main subject

cell biology

0 references

0 references

Leucine rich repeat containing G protein-coupled receptor 5

1 reference

GOA release 2020-03-11

author

Herbert Kim Lyerly

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

4

Marc G Caron

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Joshua C Snyder

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Lauren K Rochelle

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Lawrence S Barak

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

English

0 references

publication date

25 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

number of pages

12

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

10286-10297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor

24 February 2020

cites work

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LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling

19 March 2017

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

19 March 2017

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R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

19 March 2017

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Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway

19 March 2017

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A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

19 March 2017

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Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer

19 March 2017

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Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network

19 March 2017

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Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha

19 March 2017

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Rab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor

19 March 2017

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Rab11 regulates recycling through the pericentriolar recycling endosome

19 March 2017

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EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

19 March 2017

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Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus

19 March 2017

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Identification of stem cells in small intestine and colon by marker gene Lgr5

19 March 2017

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

19 March 2017

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Crypt stem cells as the cells-of-origin of intestinal cancer

19 March 2017

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Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.

19 March 2017

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Recycle your receptors with retromer

19 March 2017

1 reference

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Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*

19 March 2017

1 reference

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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

19 March 2017

1 reference

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Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

19 March 2017

1 reference

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Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Retrograde transport from endosomes to the trans-Golgi network

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Modulating neuromodulation by receptor membrane traffic in the endocytic pathway

7 April 2017

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Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

27 September 2017

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Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer

27 September 2017

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LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

27 September 2017

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Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin.

27 September 2017

1 reference

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Retromer terminates the generation of cAMP by internalized PTH receptors

27 September 2017

1 reference

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CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network

27 September 2017

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Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids

27 September 2017

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Multiple routes of protein transport from endosomes to the trans Golgi network

27 September 2017

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Reparative capacity of airway epithelium impacts deposition and remodeling of extracellular matrix

27 September 2017

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Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator

27 September 2017

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Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Desensitization of G protein-coupled receptors and neuronal functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624412

Immune evasion by adenovirus E3 proteins: exploitation of intracellular trafficking pathways.

27 September 2017

1 reference

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Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors

27 September 2017

1 reference

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Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells

27 September 2017

1 reference

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Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus

27 September 2017

1 reference

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Hierarchical phosphorylation of delta-opioid receptor regulates agonist-induced receptor desensitization and internalization

27 September 2017

1 reference

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Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

27 September 2017

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Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways

27 September 2017

1 reference

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Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation

27 September 2017

1 reference

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An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells.

27 September 2017

1 reference

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A peripheral protein associated with the cis-Golgi network redistributes in the intermediate compartment upon brefeldin A treatment

27 September 2017

1 reference

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Sequence alignment of the G-protein coupled receptor superfamily

27 September 2017

1 reference

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Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization

27 September 2017

1 reference

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Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland

27 September 2017

1 reference

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The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.447540

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.447540

Termination of protease-activated receptor-1 signaling by beta-arrestins is independent of receptor phosphorylation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.447540

beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation

21 January 2018

1 reference

12 December 2020

A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation

1 reference

12 December 2020

Calcium phosphate transfection

1 reference

12 December 2020

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

1 reference

12 December 2020

Molecular profile of organ culture-stored corneal epithelium: LGR5 is a potential new phenotypic marker of residual human corneal limbal epithelial stem cells

1 reference

12 December 2020

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.447540

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23439653%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

23439653

2 references