Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA (Q24320299)

GOA release 2020-03-11

mRNA export from nucleus

1 reference

GOA release 2020-03-11

author

Ed Hurt

3

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author name string

Jun Katahira

1

0 references

Hitomi Inoue

2

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Yoshihiro Yoneda

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

4

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language of work or name

English

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publication date

4 March 2009

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published in

The EMBO Journal

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volume

28

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page(s)

556-67

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issue

5

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cites work

1 reference

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Human mRNA export machinery recruited to the 5' end of mRNA

19 March 2017

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Recruitment of the human TREX complex to mRNA during splicing

19 March 2017

1 reference

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A molecular link between SR protein dephosphorylation and mRNA export

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

TREX is a conserved complex coupling transcription with messenger RNA export

19 March 2017

1 reference

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Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor

19 March 2017

1 reference

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TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture

19 March 2017

1 reference

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The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

19 March 2017

1 reference

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The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export

19 March 2017

1 reference

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Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The RNA polymerase II CTD kinase Ctk1 functions in translation elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2.

19 March 2017

1 reference

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Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex

19 March 2017

1 reference

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The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Exporting RNA from the nucleus to the cytoplasm

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Definition of global and transcript-specific mRNA export pathways in metazoans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Simple fold composition and modular architecture of the nuclear pore complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

TREX, SR proteins and export of mRNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Cotranscriptional mRNP assembly: from the DNA to the nuclear pore

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Identification and functional analysis of consensus androgen response elements in human prostate cancer cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

A conserved mRNA export machinery coupled to pre-mRNA splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Intron-independent association of splicing factors with active genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Cloning of a novel, anonymous gene from a megabase-range YAC and cosmid contig in the neurofibromatosis type 2/meningioma region on human chromosome 22q12.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

5' untranslated leader sequences of eukaryotic mRNAs encoding heat shock induced proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

Inactivation of splicing factors in HeLa cells subjected to heat shock.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657587

The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.5

Internal ribosome entry site drives cap-independent translation of reaper and heat shock protein 70 mRNAs in Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.5

SR splicing factors serve as adapter proteins for TAP-dependent mRNA export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.5

Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.5

The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA

21 January 2018

1 reference

12 December 2020

Translational control of protein synthesis in response to heat shock in D. melanogaster cells

1 reference

12 December 2020

Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF-4E and eIF-4 gamma

1 reference

12 December 2020

Regulation of mRNA export in response to stress in Saccharomyces cerevisiae

1 reference

12 December 2020

Optimization of nuclear transcript detection by FISH and combination with fluorescence immunocytochemical detection of transcription factors

1 reference

12 December 2020

The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export

1 reference

12 December 2020

Synchronicity: policing multiple aspects of gene expression by Ctk1

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.5

1 reference

3226782

3226782

1 reference

1 reference

1 reference