Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A (Q24317436)

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English	Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A	scientific article

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scholarly article

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17 January 2020

Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A (English)

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17 January 2020

cytochrome P450 family 2 subfamily A member 6

1 reference

GOA release 2020-03-11

cytochrome P450 family 2 subfamily C member 9

1 reference

GOA release 2020-03-11

cytochrome P450 family 1 subfamily A member 2

1 reference

GOA release 2020-03-11

cytochrome P450 family 2 subfamily B member 6

1 reference

GOA release 2020-03-11

cytochrome P450 family 2 subfamily C member 19

1 reference

GOA release 2020-03-11

xenobiotic catabolic process

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GOA release 2020-03-11

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based on heuristic

inferred from title

Seong-Wook Jeong

1

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17 January 2020

Zeruesenay Desta

3

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Zeruesenay Desta

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17 January 2020

author name string

Phuong D Nguyen

2

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24 November 2008

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17 January 2020

Antimicrobial Agents and Chemotherapy

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17 January 2020

53

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17 January 2020

541-551

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17 January 2020

2

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17 January 2020

Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A

1 reference

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19 March 2017

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

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19 March 2017

Clinical significance of the cytochrome P450 2C19 genetic polymorphism

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19 March 2017

In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6

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19 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 April 2017

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance

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27 September 2017

Voriconazole : a review of its use in the management of invasive fungal infections

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27 September 2017

Drug interaction studies: study design, data analysis, and implications for dosing and labeling

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27 September 2017

The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico.

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27 September 2017

Pharmacokinetic/pharmacodynamic profile of voriconazole

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27 September 2017

Drug metabolism and variability among patients in drug response

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27 September 2017

Clinical consequences of cytochrome P450 2C9 polymorphisms

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27 September 2017

Voriconazole: in the treatment of invasive aspergillosis

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27 September 2017

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

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27 September 2017

Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

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27 September 2017

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

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27 September 2017

Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole

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27 September 2017

Pharmacokinetic interaction between voriconazole and methadone at steady state in patients on methadone therapy

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30 May 2018

Effects of the antifungals voriconazole and fluconazole on the pharmacokinetics of s-(+)- and R-(-)-Ibuprofen

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30 May 2018

Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil

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30 May 2018

Voriconazole potentiates warfarin‐induced prothrombin time prolongation

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30 May 2018

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

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30 May 2018

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

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30 May 2018

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

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30 May 2018

Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver

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30 May 2018

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

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30 May 2018

Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation

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30 May 2018

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

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30 May 2018

Voriconazole drastically increases exposure to oral oxycodone

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29 November 2018

Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib

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29 November 2018

Role of CYP2B6 in stereoselective human methadone metabolism

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29 November 2018

Effect of voriconazole on the pharmacokinetics of diclofenac

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29 November 2018

Pharmacokinetic interaction between voriconazole and efavirenz at steady state in healthy male subjects

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29 November 2018

Effect of voriconazole and fluconazole on the pharmacokinetics of intravenous fentanyl

1 reference

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29 November 2018

Voriconazole and fluconazole increase the exposure to oral diazepam.

1 reference

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29 November 2018

Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro.

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29 November 2018

Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.

1 reference

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29 November 2018

Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa

1 reference

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29 November 2018

Voriconazole, but not terbinafine, markedly reduces alfentanil clearance and prolongs its half-life.

1 reference

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29 November 2018

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

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29 November 2018

Safety and pharmacokinetics of coadministered voriconazole and anidulafungin

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29 November 2018

Drug-drug interaction of antifungal drugs

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29 November 2018

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes

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29 November 2018

Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes

1 reference

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29 November 2018

The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation

1 reference

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29 November 2018

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

1 reference

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29 November 2018

Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis

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29 November 2018

Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration

1 reference

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29 November 2018

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

Identification of the Cytochrome P450 Enzymes Involved in theN-Oxidation of Voriconazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans

1 reference

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29 November 2018

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

1 reference

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29 November 2018

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630638

29 November 2018

Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of omeprazole and lansoprazole as inhibitors of cytochrome P450 isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of human cytochrome P450 isoforms interacting with pimozide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of CYP2C19 gene are associated with the efficacy of thalidomide based regimens in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Terbinafine and Voriconazole on the Pharmacokinetics of the Antidepressant Venlafaxine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voriconazole: a new triazole antifungal agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01123-08

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Consolidated OpenCitations Corpus – April 2017

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17 January 2020

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