Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin (Q24317170)

positive regulation of cell population proliferation

1 reference

Lymphoid enhancer binding factor 1

1 reference

POU domain, class 3, transcription factor 2

1 reference

Catenin (cadherin associated protein), beta 1

1 reference

Suzanne Carreira

5

0 references

Colin R. Goding

object named as

Colin R Goding

7

0 references

Jane Goodall

1

object named as

Jane Goodall

0 references

author name string

Silvia Martinozzi

2

0 references

Timothy J Dexter

3

0 references

Delphine Champeval

4

0 references

Lionel Larue

Molecular and Cellular Biology

6

0 references

language of work or name

English

0 references

publication date

April 2004

0 references

published in

0 references

volume

24

0 references

issue

7

0 references

page(s)

2915-22

0 references

cites work

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

19 March 2017

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Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors

19 March 2017

1 reference

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Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins

19 March 2017

1 reference

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Positive and negative elements regulate a melanocyte-specific promoter

19 March 2017

1 reference

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Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity

19 March 2017

1 reference

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Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

19 March 2017

1 reference

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Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

19 March 2017

1 reference

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Mutations of the BRAF gene in human cancer

19 March 2017

1 reference

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The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

19 March 2017

1 reference

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Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival

19 March 2017

1 reference

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Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF

19 March 2017

1 reference

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Regulation of LEF-1/TCF transcription factors by Wnt and other signals

19 March 2017

1 reference

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

19 March 2017

1 reference

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Functional interaction of beta-catenin with the transcription factor LEF-1

19 March 2017

1 reference

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

19 March 2017

1 reference

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Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2

19 March 2017

1 reference

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A helix-loop-helix transcription factor-like gene is located at the mi locus

19 March 2017

1 reference

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The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells

19 March 2017

1 reference

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The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression

19 March 2017

1 reference

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Wnt signaling: a common theme in animal development

19 March 2017

1 reference

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

7 April 2017

1 reference

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

7 April 2017

1 reference

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Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas.

7 April 2017

1 reference

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Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells

27 September 2017

1 reference

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High frequency of BRAF mutations in nevi

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Melanocyte development and malignant melanoma

27 September 2017

1 reference

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Insights into the Merkel cell phenotype from Merkel cell carcinoma cell lines

27 September 2017

1 reference

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Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development.

27 September 2017

1 reference

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Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.

27 September 2017

1 reference

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Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Control of neural crest cell fate by the Wnt signalling pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

The incidence of malignant melanoma in the United States: issues as we approach the 21st century

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Melanocyte-specific gene expression: role of repression and identification of a melanocyte-specific factor, MSF.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Malignant melanoma: modern black plague and genetic black box.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Wnt signalling required for expansion of neural crest and CNS progenitors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Human small cell lung cancer expresses the octamer DNA-binding and nervous system-specific transcription factor N-Oct 3 (brain-2)

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Lack of BRAF mutations in uveal melanoma

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Lack of BRAF mutation in primary uveal melanoma.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Primary brain tumors differ in their expression of octamer deoxyribonucleic acid-binding transcription factors from long-term cultured glioma cell lines.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371132

Reconstitution of T cell-specific transcription directed by composite NFAT/Oct elements

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15024079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Constitutive activation of Wnt/beta-catenin signaling pathway in migration-active melanoma cells: role of LEF-1 in melanoma with increased metastatic potential

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15024079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Absence of BRAF and NRAS mutations in uveal melanoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15024079