Inhibition of beta A4 production by specific modulation of beta-secretase activity (Q24317112)

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14 October 2019

title

Inhibition of beta A4 production by specific modulation of beta-secretase activity (English)

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14 October 2019

1 reference

GOA release 2020-03-11

peptidase activity

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GOA release 2020-03-11

author

Christian Czech

4

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14 October 2019

author name string

B Urmoneit

1

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14 October 2019

C Reinsch

2

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14 October 2019

J Turner

3

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14 October 2019

K Beyreuther

5

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14 October 2019

T Dyrks

6

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14 October 2019

language of work or name

English

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publication date

1 January 1995

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Journal of Molecular Neuroscience

14 October 2019

published in

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14 October 2019

volume

6

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14 October 2019

issue

1

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14 October 2019

page(s)

23-32

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Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells

14 October 2019

cites work

1 reference

12 December 2020

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

12 December 2020

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

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Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

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12 December 2020

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

12 December 2020

Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.

1 reference

12 December 2020

Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate

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12 December 2020

Generation of beta A4 from the amyloid protein precursor and fragments thereof

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12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

12 December 2020

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

12 December 2020

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

12 December 2020

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

12 December 2020

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

12 December 2020

Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive

1 reference

12 December 2020

Evidence for a nonsecretory, acidic degradation pathway for amyloid precursor protein in 293 cells. Identification of a novel, 22-kDa, beta-peptide-containing intermediate

1 reference

12 December 2020