Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1) (Q24316057)

solute:proton symporter activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Bryan Mackenzie

1

0 references

Hitomi Takanaga

2

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Nadia Hubert

3

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Andreas Rolfs

4

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Matthias A Hediger

Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain

5

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language of work or name

English

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publication date

1 April 2007

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published in

Biochemical Journal

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volume

403

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page(s)

59-69

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issue

1

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cites work

1 reference

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19 March 2017

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A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway

19 March 2017

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Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms

19 March 2017

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Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

19 March 2017

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Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes

19 March 2017

1 reference

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Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes

19 March 2017

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Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

19 March 2017

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SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1

19 March 2017

1 reference

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The sodium/glucose cotransport family SLC5

19 March 2017

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Intestinal expression of genes involved in iron absorption in humans

19 March 2017

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Iron-dependent regulation of the divalent metal ion transporter

19 March 2017

1 reference

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Yeast SMF1 mediates H(+)-coupled iron uptake with concomitant uncoupled cation currents

19 March 2017

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PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

19 March 2017

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The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms

19 March 2017

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

19 March 2017

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Expression cloning and cDNA sequencing of the Na+/glucose co-transporter

19 March 2017

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Noncomplexing Tertiary Amines as “Better” Buffers Covering the Range of pH 3−11. Temperature Dependence of Their Acid Dissociation Constants

19 March 2017

1 reference

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Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence

24 March 2017

1 reference

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Balancing acts: molecular control of mammalian iron metabolism

7 April 2017

1 reference

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Comparison of mammalian cell lines expressing distinct isoforms of divalent metal transporter 1 in a tetracycline-regulated fashion

7 April 2017

1 reference

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Iron Imports. II. Iron uptake at the apical membrane in the intestine

27 September 2017

1 reference

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The neuronal glycine transporter 2 interacts with the PDZ domain protein syntenin-1.

27 September 2017

1 reference

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Iron metabolism and the IRE/IRP regulatory system: an update

27 September 2017

1 reference

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Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons.

27 September 2017

1 reference

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Better prediction of protein cellular localization sites with the k nearest neighbors classifier.

27 September 2017

1 reference

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Induction of endogenous channels by high levels of heterologous membrane proteins in Xenopus oocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Avoiding interferences from Good's buffers: A contiguous series of noncomplexing tertiary amine buffers covering the entire range of pH 3-11.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Cellular localization and subcellular distribution of Unc-33-like protein 6, a brain-specific protein of the collapsin response mediator protein family that interacts with the neuronal glycine transporter 2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Computer-identified nuclear localization signal in exon 1A of the transporter DMT1 is essentially ineffective in nuclear targeting.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Modulation of DMT1 activity by redox compounds.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Properties of the mammalian and yeast metal-ion transporters DCT1 and Smf1p expressed in Xenopus laevis oocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Relationships between Na+/glucose cotransporter (SGLT1) currents and fluxes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

Presteady-state currents of the rabbit Na+/glucose cotransporter (SGLT1).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

A method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828886

DMT1: which metals does it transport?

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17109629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17109629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A combined TDDA-PVC pH and reference electrode for use in the upper small intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17109629