Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinase (Q24314907)

GOA release 2020-03-11

SRSF protein kinase 1

1 reference

positive regulation of viral genome replication

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1 reference

13

Mamoru Watanabe

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author name string

Yuko Karakama

1

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Naoya Sakamoto

2

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Yasuhiro Itsui

3

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Mina Nakagawa

4

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Megumi Tasaka-Fujita

5

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Yuki Nishimura-Sakurai

6

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Sei Kakinuma

7

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Masaya Oooka

8

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Seishin Azuma

9

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Kiichiro Tsuchiya

10

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Hiroshi Onogi

11

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Masatoshi Hagiwara

Antimicrobial Agents and Chemotherapy

12

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language of work or name

English

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publication date

August 2010

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published in

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volume

54

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issue

8

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page(s)

3179-86

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cites work

Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein

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SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

19 March 2017

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A serine kinase regulates intracellular localization of splicing factors in the cell cycle

19 March 2017

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A genome-wide genetic screen for host factors required for hepatitis C virus propagation

19 March 2017

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Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

19 March 2017

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

19 March 2017

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Robust hepatitis C virus infection in vitro

19 March 2017

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Manipulation of alternative splicing by a newly developed inhibitor of Clks

19 March 2017

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Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

19 March 2017

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Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

19 March 2017

1 reference

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Effect of alpha interferon on the hepatitis C virus replicon

19 March 2017

1 reference

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Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

19 March 2017

1 reference

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Epidemiology of hepatitis C

19 March 2017

1 reference

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SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors

19 March 2017

1 reference

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Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

19 March 2017

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Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells

7 April 2017

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Antiviral resistance and specifically targeted therapy for HCV (STAT-C).

27 September 2017

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New therapeutic approaches to hepatitis C virus

27 September 2017

1 reference

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Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity

27 September 2017

1 reference

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Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication

27 September 2017

1 reference

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Utilization of host SR protein kinases and RNA-splicing machinery during viral replication

27 September 2017

1 reference

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Ceramide regulates SR protein phosphorylation during adenoviral infection.

27 September 2017

1 reference

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Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Specific inhibition of hepatitis C virus replication by cyclosporin A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1.

27 September 2017

1 reference

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The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

The SR protein family: pleiotropic functions in pre-mRNA splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Bone morphogenetic protein-7 and interferon-alpha synergistically suppress hepatitis C virus replicon

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916360