Functional analysis of the human TAFII250 N-terminal kinase domain (Q24314832)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

1 reference

A novel tumour marker related to the c-myc oncogene product

GOA release 2020-03-11

author name string

T O'Brien

series ordinal

1

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R Tjian

series ordinal

2

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language of work or name

English

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publication date

May 1998

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published in

Molecular Cell

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volume

1

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page(s)

905-11

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issue

6

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cites work

1 reference

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Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

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TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74

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TBP-TAF complexes: selectivity factors for eukaryotic transcription

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Transcription properties of a cell type-specific TATA-binding protein, TRF.

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The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster

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7 January 2021

The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1.

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7 January 2021

The TAF(II)250 subunit of TFIID has histone acetyltransferase activity

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Minimum essential region of CCG1/TAFII250 required for complementing the temperature-sensitive cell cycle mutants, tsBN462 and ts13 cells, of hamster BHK21 cells.

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The general transcription factors of RNA polymerase II

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Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

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Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation

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Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation

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7 January 2021

Multiple TAFIIs directing synergistic activation of transcription

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Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor

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The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein

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7 January 2021

The ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature

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Temperature sensitive mutants of BHK cells affected in cell cycle progression

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Dimerization of TFIID when not bound to DNA.

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p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

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Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II.

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TAFII250-dependent transcription of cyclin A is directed by ATF activator proteins

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Promoter-selective transcriptional defect in cell cycle mutant ts13 rescued by hTAFII250.

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Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator.

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7 January 2021