Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B (Q24314709)

cell population proliferation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

R Cipriano

1

0 references

B L Bryson

2

0 references

K L S Miskimen

3

0 references

C A Bartel

4

0 references

W Hernandez-Sanchez

5

0 references

R C Bruntz

6

0 references

S A Scott

7

0 references

C W Lindsley

8

0 references

H A Brown

9

0 references

M W Jackson

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies

10

0 references

language of work or name

English

0 references

publication date

19 June 2014

0 references

published in

Oncogene

0 references

volume

33

0 references

issue

25

0 references

page(s)

3298-306

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice

19 March 2017

1 reference

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FAM83B mediates EGFR- and RAS-driven oncogenic transformation

19 March 2017

1 reference

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Role of phosphatidic acid in the coupling of the ERK cascade

19 March 2017

1 reference

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New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists

19 March 2017

1 reference

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Defining the role of mTOR in cancer

19 March 2017

1 reference

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Phospholipase D in cell proliferation and cancer

19 March 2017

1 reference

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

19 March 2017

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

7 April 2017

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Phospholipase D: enzymology, functionality, and chemical modulation

7 April 2017

1 reference

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Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis

27 September 2017

1 reference

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Survival outcomes for patients with metastatic triple-negative breast cancer: implications for clinical practice and trial design

27 September 2017

1 reference

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Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells

27 September 2017

1 reference

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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

27 September 2017

1 reference

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Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin

27 September 2017

1 reference

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Cotargeting survival signaling pathways in cancer

27 September 2017

1 reference

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Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model

27 September 2017

1 reference

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Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras

27 September 2017

1 reference

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Regulation of mTOR by phosphatidic acid?

27 September 2017

1 reference

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RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

27 September 2017

1 reference

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Requirement of phospholipase D1 activity in H-RasV12-induced transformation

27 September 2017

1 reference

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Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

27 September 2017

1 reference

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Transformation of cells overexpressing a tyrosine kinase by phospholipase D1 and D2.

27 September 2017

1 reference

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RalA mediates v-Src, v-Ras, and v-Raf regulation of CD44 and fibronectin expression in NIH3T3 fibroblasts

27 September 2017

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Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

Regulation of Raf-1 kinase by interaction with the lipid second messenger, phosphatidic acid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

p53-mediated growth suppression in response to Nutlin-3 in cyclin D1 transformed cells occurs independently of p21.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

Association of N- and C-terminal domains of phospholipase D is required for catalytic activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923847

The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Biochemical analysis of phospholipase D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Phospholipase D confers rapamycin resistance in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Cotargeting survival signaling pathways in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Species- and cell type-specific requirements for cellular transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Targeting Phospholipase D-mediated Survival Signals in Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Increased phospholipase D activity in human breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Overexpression of phospholipase D1 in human breast cancer tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.293

Phospholipase D activity in human gastric carcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23912460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.293

1 reference

Dimensions Publication ID

4825207

1037936334

0 references

4825207

1 reference

1 reference

1 reference