LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease (Q24314512)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17098871%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease (English)

1 reference

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21 December 2019

2

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21 December 2019

Dirk Beher

22

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21 December 2019

11

Berta Strulovici

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21 December 2019

author name string

John Majercak

1

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21 December 2019

Amy Espeseth

3

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21 December 2019

Adam Simon

4

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21 December 2019

Xiao-Ping Shi

5

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21 December 2019

Carrie Wolffe

6

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21 December 2019

Krista Getty

7

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21 December 2019

Shane Marine

8

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21 December 2019

Erica Stec

9

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21 December 2019

Marc Ferrer

10

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21 December 2019

Steven Bartz

12

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21 December 2019

Adam Gates

13

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21 December 2019

Min Xu

14

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21 December 2019

Qian Huang

15

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21 December 2019

Lei Ma

16

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21 December 2019

Paul Shughrue

17

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21 December 2019

Julja Burchard

18

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21 December 2019

Dennis Colussi

19

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21 December 2019

Beth Pietrak

20

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21 December 2019

Jason Kahana

21

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21 December 2019

Thomas Rosahl

23

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21 December 2019

Mark Shearman

24

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21 December 2019

Daria Hazuda

25

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21 December 2019

Alan B Sachs

26

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21 December 2019

Kenneth S Koblan

27

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21 December 2019

Guy R Seabrook

28

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21 December 2019

David J Stone

29

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21 December 2019

language of work or name

English

0 references

publication date

10 November 2006

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

21 December 2019

published in

1 reference

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21 December 2019

volume

103

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21 December 2019

page(s)

17967-17972

1 reference

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21 December 2019

issue

47

1 reference

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A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

21 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635650

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

19 March 2017

1 reference

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A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system

19 March 2017

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Deciphering the genetic basis of Alzheimer's disease

19 March 2017

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Cadherin superfamily genes: functions, genomic organization, and neurologic diversity

19 March 2017

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

19 March 2017

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Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease

7 April 2017

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Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

27 September 2017

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AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs

27 September 2017

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Apolipoprotein E, amyloid, and Alzheimer disease

27 September 2017

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Fine mapping of the -T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

27 September 2017

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Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology

27 September 2017

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A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease

27 September 2017

1 reference

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The role of A beta 42 in Alzheimer's disease

30 May 2018

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Life and death of neurons in the aging brain

30 May 2018

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Reconstitution of gamma-secretase activity

30 May 2018

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

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Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

21 January 2018

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alpha- and beta-secretase: profound changes in Alzheimer's disease.

21 January 2018

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Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

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Methods to enhance signal using isotopic in situ hybridization

21 January 2018

1 reference

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Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease

21 January 2018

1 reference

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Full genome screen for Alzheimer disease: Stage II analysis

21 January 2018

1 reference

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Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.

21 January 2018

1 reference

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Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.

29 November 2018

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Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

29 November 2018

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Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17098871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0605461103

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17098871%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

ADS bibcode

2006PNAS..10317967M

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17098871%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

2 references