Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling (Q24313378)

GOA release 2020-03-11

Ankyrin 3, epithelial

1 reference

GOA release 2020-03-11

3

Henrik Dimke

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author name string

Pedro San-Cristobal

1

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Sergio Lainez

2

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Mark J J de Graaf

4

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Joost G J Hoenderop

5

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René J M Bindels

Novel molecular pathways in renal Mg2+ transport: a guided tour along the nephron.

6

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language of work or name

English

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publication date

January 2014

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published in

Kidney International

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volume

85

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issue

1

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page(s)

94-102

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cites work

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Hereditary tubular transport disorders: implications for renal handling of Ca2+ and Mg2+.

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Molecular basis of epithelial Ca2+ and Mg2+ transport: insights from the TRP channel family

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Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

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TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption

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Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

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A missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemia

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Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1

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Structure and function of voltage-sensitive ion channels

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Potassium channel structures

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The distribution and targeting of neuronal voltage-gated ion channels

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

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Role of the alpha-kinase domain in transient receptor potential melastatin 6 channel and regulation by intracellular ATP.

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A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport

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Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia

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Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport

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Regulation of potassium (K) handling in the renal collecting duct

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Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel

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Molecular diversity and regulation of renal potassium channels

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The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane

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Ankyrin links fodrin to the alpha subunit of Na,K-ATPase in Madin-Darby canine kidney cells and in intact renal tubule cells

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7 January 2021

A new 440-kD isoform is the major ankyrin in neonatal rat brain

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Distribution of Na+ channels and ankyrin in neuromuscular junctions is complementary to that of acetylcholine receptors and the 43 kd protein

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An isoform of ankyrin is localized at nodes of Ranvier in myelinated axons of central and peripheral nerves

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Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

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Ankyrin binding to (Na+ + K+)ATPase and implications for the organization of membrane domains in polarized cells

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Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment

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7 January 2021

Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains

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7 January 2021

Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150

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7 January 2021

The epithelial Mg2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg2+ content and estrogens

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γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter

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CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia

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7 January 2021