ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation (Q24311818)

microtubule associated protein tau

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

apolipoprotein binding

1 reference

GOA release 2020-03-11

1 reference

1 reference

D Y Huang

1

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K H Weisgraber

2

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M Goedert

3

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A M Saunders

4

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A D Roses

5

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W J Strittmatter

Tau proteins are abnormally expressed in olfactory epithelium of Alzheimer patients and developmentally regulated in human fetal spinal cord.

6

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language of work or name

English

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publication date

16 June 1995

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published in

Neuroscience Letters

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volume

192

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page(s)

209-12

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issue

3

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cites work

1 reference

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7 January 2021

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

1 reference

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7 January 2021

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.

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7 January 2021

Isolation and characterization of apolipoprotein E

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7 January 2021

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.

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7 January 2021

Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.

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7 January 2021

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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7 January 2021

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

1 reference

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7 January 2021

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

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7 January 2021

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

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7 January 2021

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

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7 January 2021

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

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7 January 2021

Tau phosphorylation in human, primate, and rat brain: evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro.

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7 January 2021

Tau protein binds to microtubules through a flexible array of distributed weak sites

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7 January 2021

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

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7 January 2021

Solid-phase synthesis of a range of O-phosphorylated peptides by post-assembly phosphitylation and oxidation

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7 January 2021

Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

1 reference

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7 January 2021

Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein.

1 reference

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7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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7 January 2021

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

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7 January 2021