Crystallographic insights into sodium-channel modulation by the β4 subunit (Q24310927)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Crystallographic insights into sodium-channel modulation by the β4 subunit (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

Sodium voltage-gated channel beta subunit 4

2 March 2020

main subject

1 reference

regulation of sodium ion transmembrane transporter activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Filip Van Petegem

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Frank Bosmans

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Frank Bosmans

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Samir Das

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

2 December 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

2 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

110

1 reference

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2 March 2020

issue

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

E5016-24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

Sudden infant death syndrome-associated mutations in the sodium channel beta subunits

2 March 2020

cites work

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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

19 March 2017

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SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

19 March 2017

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Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2

19 March 2017

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beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics

19 March 2017

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19 March 2017

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Crystal structure of the extracellular domain of human myelin protein zero

19 March 2017

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19 March 2017

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19 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

19 March 2017

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19 March 2017

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International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

22 April 2017

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Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1

19 March 2017

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Intrinsic lidocaine affinity for Na channels expressed in Xenopus oocytes depends on alpha (hH1 vs. rSkM1) and beta 1 subunits

19 March 2017

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Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

19 March 2017

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Splice variants of Na(V)1.7 sodium channels have distinct β subunit-dependent biophysical properties

19 March 2017

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Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons

19 March 2017

1 reference

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Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif

19 March 2017

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Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.

19 March 2017

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Na+ channel-dependent recruitment of Navβ4 to axon initial segments and nodes of Ranvier

27 September 2017

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Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5.

27 September 2017

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The Na(V)1.7 sodium channel: from molecule to man.

27 September 2017

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Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins

27 September 2017

1 reference

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The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding

27 September 2017

1 reference

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Modulation of voltage-gated K+ channels by the sodium channel β1 subunit

27 September 2017

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Identification of the cysteine residue responsible for disulfide linkage of Na+ channel α and β2 subunits

27 September 2017

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Glycosylation of the sodium channel β4 subunit is developmentally regulated and involves in neuritic degeneration

27 September 2017

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The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.

27 September 2017

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Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons

27 September 2017

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Na Channel β Subunits: Overachievers of the Ion Channel Family

27 September 2017

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Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy

27 September 2017

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Navβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIB

27 September 2017

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New mutation c.374C>T and a putative disease-associated haplotype within SCN1B gene in Tunisian families with febrile seizures

27 September 2017

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The Tarantula Toxins ProTx-II and Huwentoxin-IV Differentially Interact with Human Nav1.7 Voltage Sensors to Inhibit Channel Activation and Inactivation

27 September 2017

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Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus

27 September 2017

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A functional null mutation of SCN1B in a patient with Dravet syndrome

27 September 2017

1 reference

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Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels

27 September 2017

1 reference

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A novel adhesion molecule in human breast cancer cells: voltage-gated Na+ channel beta1 subunit.

27 September 2017

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Deconstructing voltage sensor function and pharmacology in sodium channels

27 September 2017

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27 September 2017

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Beta-subunits of voltage-gated sodium channels in human prostate cancer: quantitative in vitro and in vivo analyses of mRNA expression.

27 September 2017

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Inherited disorders of voltage-gated sodium channels

27 September 2017

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beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

27 September 2017

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Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

27 September 2017

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Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements

27 September 2017

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Lidocaine block of neonatal Nav1.3 is differentially modulated by co-expression of β1 and β3 subunits

27 September 2017

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Two tarantula peptides inhibit activation of multiple sodium channels

27 September 2017

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Ion pairs and the thermotolerance of proteins from hyperthermophiles: a "traffic rule" for hot roads

27 September 2017

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Cloning, localization, and functional expression of sodium channel beta1A subunits

27 September 2017

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Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms

27 September 2017

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Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

27 September 2017

1 reference

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A rat brain Na+ channel alpha subunit with novel gating properties

27 September 2017

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Isolation and characterisation of three polypeptides with neurotoxic activity from Anemonia sulcata

27 September 2017

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The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

27 September 2017

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The sodium channel {beta}3-subunit induces multiphasic gating in NaV1.3 and affects fast inactivation via distinct intracellular regions

27 September 2017

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Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.

30 May 2018

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Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit

30 May 2018

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Molecular determinants of beta 1 subunit-induced gating modulation in voltage-dependent Na+ channels.

30 May 2018

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Mechanism of modulation of single sodium channels from skeletal muscle by the beta 1-subunit from rat brain.

30 May 2018

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Large scale purification of toxins from the venom of the scorpion Androctonus australis Hector

30 May 2018

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The correlation between Na+ channel subunits and scorpion toxin-binding sites. A study in rat brain synaptosomes and in brain neurons developing in vitro

30 May 2018

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Purification of the main beta-toxin from Tityus serrulatus scorpion venom using high-performance liquid chromatography

30 May 2018

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Tetraspanin proteins promote multiple cancer stages

30 May 2018

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Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice

21 January 2018

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Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currents

21 January 2018

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Effects of Tityus serrulatus scorpion toxin gamma on voltage-gated Na+ channels

21 January 2018

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Temporal lobe epilepsy and GEFS+ phenotypes associated with SCN1B mutations.

21 January 2018

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A homozygous mutation of voltage-gated sodium channel β(I) gene SCN1B in a patient with Dravet syndrome

21 January 2018

1 reference

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A thermoprotective role of the sodium channel β1 subunit is lost with the β1 (C121W) mutation

21 January 2018

1 reference

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Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits

21 January 2018

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Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxol

21 January 2018

1 reference

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The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching

21 January 2018

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Mutations of the SCN4B-encoded sodium channel β4 subunit in familial atrial fibrillation.

21 January 2018

1 reference

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The voltage-gated Na+ channel Nav1.8 contains an ER-retention/retrieval signal antagonized by the beta3 subunit

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24297919

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Voltage-gated Na+ channels: potential for beta subunits as therapeutic targets

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24297919

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1314557110

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

ADS bibcode

2013PNAS..110E5016G

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24297919

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24297919%20AND%20SRC:MED&resulttype=core&format=json