Ubiquitination of CXCR7 controls receptor trafficking (Q24310278)

Atypical chemokine receptor 3

1 reference

Arrestin beta 2

1 reference

C-X-C motif chemokine ligand 12

1 reference

positive regulation of receptor internalization

1 reference

protein ubiquitination

1 reference

Danny J Scholten

2

0 references

Meritxell Canals

object named as

Meritxell Canals

1

0 references

author name string

Sabrina de Munnik

3

0 references

Mitchell K L Han

4

0 references

Martine J Smit

5

0 references

Rob Leurs

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

0 references

page(s)

e34192

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issue

3

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copyright license

start time

23 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation

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19 March 2017

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beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

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Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

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CXCR7 functions as a scavenger for CXCL12 and CXCL11

19 March 2017

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AMD3100 is a CXCR7 ligand with allosteric agonist properties

19 March 2017

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Control of chemokine-guided cell migration by ligand sequestration

19 March 2017

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The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

19 March 2017

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The CXCR7 chemokine receptor promotes B-cell retention in the splenic marginal zone and serves as a sink for CXCL12.

19 March 2017

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CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

27 September 2017

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The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells

27 September 2017

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Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains

27 September 2017

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27 September 2017

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Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4

27 September 2017

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Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling

27 September 2017

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Imaging ligand-dependent activation of CXCR7.

27 September 2017

1 reference

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Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands

27 September 2017

1 reference

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Derailed endocytosis: an emerging feature of cancer

27 September 2017

1 reference

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Viral hijacking of human receptors through heterodimerization

27 September 2017

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Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics.

27 September 2017

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Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors

27 September 2017

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Regulation of GPCRs by endocytic membrane trafficking and its potential implications

27 September 2017

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Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

27 September 2017

1 reference

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Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

27 September 2017

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Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1

27 September 2017

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Seven-transmembrane receptors and ubiquitination

27 September 2017

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Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

27 September 2017

1 reference

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Chemokine receptor internalization and intracellular trafficking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Real-time monitoring of ubiquitination in living cells by BRET.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Modulation of the arrestin-clathrin interaction in cells. Characterization of beta-arrestin dominant-negative mutants

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

CXCR7 mediated Giα independent activation of ERK and Akt promotes cell survival and chemotaxis in T cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Activation of CXCR7 receptor promotes oligodendroglial cell maturation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311620

Mechanisms of desensitization and resensitization of G protein-coupled neurokinin1 and neurokinin2 receptors.

29 November 2018

1 reference

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Nonspecific CXCR7 antibodies

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22457824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cxcr7 Controls Neuronal Migration by Regulating Chemokine Responsiveness

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22457824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22457824