Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity (Q24309446)

testosterone 17-beta-dehydrogenase (NADP+) activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Udo Oppermann

9

0 references

Jerzy Adamski

8

0 references

author name string

Petra Lukacik

1

0 references

Brigitte Keller

2

0 references

Gabor Bunkoczi

3

0 references

Kathryn L Kavanagh

4

0 references

Kathryn Kavanagh

5

0 references

Wen Hwa Lee

Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology

6

0 references

language of work or name

English

0 references

publication date

15 March 2007

0 references

published in

Biochemical Journal

0 references

volume

402

0 references

issue

3

0 references

page(s)

419-27

0 references

cites work

1 reference

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Isolation and characterization of cDNA for human 120 kDa mitochondrial 2,4-dienoyl-coenzyme A reductase

19 March 2017

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The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors

19 March 2017

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19 March 2017

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Maximum-likelihood density modification

19 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3)

19 March 2017

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Short-chain dehydrogenases/reductases in retina

19 March 2017

1 reference

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Molecular cloning and characterization of the human mitochondrial 2,4-dienoyl-CoA reductase gene (DECR)

19 March 2017

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Short-chain dehydrogenases/reductases (SDR)

19 March 2017

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Structure and function of human 17beta-hydroxysteroid dehydrogenases

7 April 2017

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Estrogen activates classical and alternative mechanisms to orchestrate neuroprotection

27 September 2017

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27 September 2017

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Estrogen and cognition, with a focus on Alzheimer's disease

27 September 2017

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Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative

27 September 2017

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Estrogen and the brain: beyond ER-alpha and ER-beta

27 September 2017

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27 September 2017

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Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue

27 September 2017

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27 September 2017

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ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury.

27 September 2017

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Estrogen actions in the brain

27 September 2017

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The hypothalamic-pituitary-gonadal axis in mood disorders

27 September 2017

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Critical residues for structure and catalysis in short-chain dehydrogenases/reductases

27 September 2017

1 reference

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Metabolic conversion as a pre-receptor control mechanism for lipophilic hormones

27 September 2017

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High-throughput docking for lead generation

27 September 2017

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Forms and functions of human SDR enzymes

27 September 2017

1 reference

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A guide to 17beta-hydroxysteroid dehydrogenases

27 September 2017

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Estrogen and the developing mammalian brain

27 September 2017

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Contact area difference (CAD): a robust measure to evaluate accuracy of protein models

27 September 2017

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Modulation of brain dopamine transmission by sex steroids

27 September 2017

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Regulation of neuropeptide gene expression by steroid hormones

27 September 2017

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Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression

27 September 2017

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Human 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression and localization in term placenta and in endometrium during the menstrual cycle.

27 September 2017

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Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue

30 May 2018

1 reference

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Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss

29 November 2018

1 reference

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Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism

29 November 2018

1 reference

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Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species

29 November 2018

1 reference

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Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7alpha-hydroxylase and 17-ketosteroid reductase activity in the human brain

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863559

Short-chain dehydrogenases/reductases (SDRs).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863559

Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863559

The aldo-keto reductase (AKR) superfamily: an update

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863559

Human liver class I alcohol dehydrogenaseγγ isozyme: the sole cytosolic 3β-hydroxysteroid dehydrogenase of iso bile acids

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863559

Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17067289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17067289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[24] Short-chain dehydrogenases/reductases in retina

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20061319