Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease (Q24308731)

lipoprotein particle binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

W J Strittmatter

1

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A M Saunders

2

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M Goedert

3

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K H Weisgraber

4

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L M Dong

5

0 references

R Jakes

6

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D Y Huang

7

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M Pericak-Vance

8

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D Schmechel

9

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A D Roses

Proceedings of the National Academy of Sciences of the United States of America

10

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language of work or name

English

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publication date

8 November 1994

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published in

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volume

91

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page(s)

11183-6

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issue

23

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cites work

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

7 April 2017

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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

27 September 2017

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Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

27 September 2017

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Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

27 September 2017

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Apolipoprotein E: structure-function relationships

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Tau protein and the neurofibrillary pathology of Alzheimer's disease

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Abnormal in vivo metabolism of apolipoprotein E4 in humans

27 September 2017

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Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

27 September 2017

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The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

27 September 2017

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Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization

27 September 2017

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27 September 2017

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Apolipoprotein E distribution among human plasma lipoproteins: role of the cysteine-arginine interchange at residue 112.

30 May 2018

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Apolipoprotein E localization in rat hepatocytes by immunogold labeling of cryothin sections

30 May 2018

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Identification of the disulfide-linked homodimer of apolipoprotein E3 in plasma. Impact on receptor binding activity

30 May 2018

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

30 May 2018

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A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

30 May 2018

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau.

29 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

beta-Amyloid precursor epitopes in muscle fibers of inclusion body myositis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45191

Apolipoprotein-E degradation in human very low density lipoproteins by plasma protease(s): chemical and biological consequences

29 November 2018

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12 December 2020

The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments

1 reference

12 December 2020

Isolation and characterization of apolipoprotein E

1 reference

12 December 2020

Apolipoprotein E immunoreactive deposits in inclusion-body muscle diseases

1 reference

12 December 2020

Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms

1 reference

12 December 2020