The tumor suppressor hTid1 inhibits STAT5b activity via functional interaction (Q24308570)

N-acylethanolamine acid amidase

1 reference

negative regulation of transcription by RNA polymerase II

1 reference

Signal transducer and activator of transcription 5B

1 reference

author name string

Isabelle Dhennin-Duthille

1

0 references

Rémy Nyga

2

0 references

Saliha Yahiaoui

3

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Valérie Gouilleux-Gruart

4

0 references

Aline Régnier

5

0 references

Kaïss Lassoued

6

0 references

Fabrice Gouilleux

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

18 February 2011

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published in

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volume

286

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issue

7

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page(s)

5034-42

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cites work

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TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions

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19 March 2017

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

19 March 2017

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Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.

7 April 2017

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Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer

27 September 2017

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The mitochondrial protein hTID-1 partners with the caspase-cleaved adenomatous polyposis cell tumor suppressor to facilitate apoptosis

27 September 2017

1 reference

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Tid1 functions as a tumour suppressor in head and neck squamous cell carcinoma

27 September 2017

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Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells

27 September 2017

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STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression

27 September 2017

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Proteasome-dependent down-regulation of activated Stat5A in the nucleus

27 September 2017

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Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation

27 September 2017

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Stat5a/b are essential for normal lymphoid development and differentiation

27 September 2017

1 reference

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Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos

27 September 2017

1 reference

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Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis.

27 September 2017

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Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells

27 September 2017

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Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation

27 September 2017

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27 September 2017

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Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli

27 September 2017

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Interleukin-7 induces apoptosis of 697 pre-B cells expressing dominant-negative forms of STAT5: evidence for caspase-dependent and -independent mechanisms.

27 September 2017

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27 September 2017

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Constitutive activation of Stat5b contributes to carcinogenesis in vivo

27 September 2017

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NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain

27 September 2017

1 reference

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TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells

27 September 2017

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27 September 2017

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STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor

27 September 2017

1 reference

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27 September 2017

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27 September 2017

1 reference

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Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

27 September 2017

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27 September 2017

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Role of Jak kinases and STATs in cytokine signal transduction

27 September 2017

1 reference

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Signal transducers and activators of transcription 5B potentiates v-Src-mediated transformation of NIH-3T3 cells

27 September 2017

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A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Cooperation between STAT5 and phosphatidylinositol 3-kinase in the IL-3-dependent survival of a bone marrow derived cell line

27 September 2017

1 reference

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Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells

27 September 2017

1 reference

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A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

27 September 2017

1 reference

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Negative regulators of cytokine signal transduction

27 September 2017

1 reference

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IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line

27 September 2017

1 reference

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

27 September 2017

1 reference

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A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein

27 September 2017

1 reference

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

27 September 2017

1 reference

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Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Stat5a serine phosphorylation. Serine 779 is constitutively phosphorylated in the mammary gland, and serine 725 phosphorylation influences prolactin-stimulated in vitro DNA binding activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Stat5a is mandatory for adult mammary gland development and lactogenesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.155903

SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.155903

Sequence, molecular organization and products of the Drosophila virilis homologs of the D. melanogaster nested genes lethal(2) tumorous imaginal discs [1(2)tid] and lethal(2) neighbour of tid [1(2)not].

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.155903

Stat5 tetramer formation is associated with leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.155903

Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037615

Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1alpha

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21106534

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.155903

0 references

Fatcat ID

release_x7wtzuiwwbe33mzoooklulakgq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x7wtzuiwwbe33mzoooklulakgq