HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells (Q24305151)

negative regulation of cell growth

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

4

Ludger Klein-Hitpass

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author name string

Karen Grigo

1

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Andrea Wirsing

2

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Belén Lucas

3

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Gerhart U Ryffel

Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer

5

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language of work or name

English

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publication date

February 2008

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published in

Biological Chemistry

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volume

389

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issue

2

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page(s)

179-87

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cites work

1 reference

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Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha

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Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line

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Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

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Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

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Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo

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Multiple-laboratory comparison of microarray platforms

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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

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Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data

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Integration of Myeloblastosis Associated Virus proviral sequences occurs in the vicinity of genes encoding signaling proteins and regulators of cell proliferation

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Focus on kidney cancer

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Identification of prodomain determinants involved in ADAMTS-1 biosynthesis

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Brain specific human genes, NELL1 and NELL2, are predominantly expressed in neuroblastoma and other embryonal neuroepithelial tumors

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Do-it-yourself RNAi made easy?

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Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells

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ADAMs in cancer cell proliferation and progression.

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Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray

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Control of pancreas and liver gene expression by HNF transcription factors

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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

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Human renal cell carcinogenesis is accompanied by a coordinate loss of the tissue specific transcription factors HNF4 alpha and HNF1 alpha.

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Expression of stress-response and cell proliferation genes in renal cell carcinoma induced by oxidative stress

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p21 is a prognostic marker for renal cell carcinoma: implications for novel therapeutic approaches.

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A plethora of epidermal growth factor-like proteins in polycystic kidneys

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HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma

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Identification of genes differentially expressed in benign prostatic hyperplasia

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Inverse mRNA expression of the selenocysteine-containing proteins GI-GPx and SeP in colorectal adenomas compared with adjacent normal mucosa

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