Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif (Q24305073)

identical protein binding

GOA release 2020-03-11

1 reference

Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20

GOA release 2020-03-11

2

Stefan Jehle

Stefan

Jehle

1 reference

19 October 2023

Scott P Delbecq

1

Scott P

Delbecq

1 reference

19 October 2023

Rachel Klevit

series ordinal

3

author given names

Rachel

author last names

Klevit

1 reference

19 October 2023

language of work or name

English

0 references

publication date

12 December 2012

0 references

published in

The EMBO Journal

0 references

volume

31

0 references

issue

24

0 references

page(s)

4587-94

0 references

cites work

1 reference

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A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

19 March 2017

1 reference

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Multiple molecular architectures of the eye lens chaperone B-crystallin elucidated by a triple hybrid approach

19 March 2017

1 reference

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Three-dimensional structure of α-crystallin domain dimers of human small heat shock proteins HSPB1 and HSPB6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

N-terminal domain of B-crystallin provides a conformational switch for multimerization and structural heterogeneity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove

19 March 2017

1 reference

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Crystal structures of Xanthomonas small heat shock protein provide a structural basis for an active molecular chaperone oligomer

19 March 2017

1 reference

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Dimer structure and conformational variability in the N-terminal region of an archaeal small heat shock protein, StHsp14.0

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Crystal structure and assembly of a eukaryotic small heat shock protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Crystal structure of a small heat-shock protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

NMR View: A computer program for the visualization and analysis of NMR data

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Molecular chaperones and protein quality control

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Alpha-crystallin can function as a molecular chaperone

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

A quantitative NMR spectroscopic examination of the flexibility of the C-terminal extensions of the molecular chaperones, αA- and αB-crystallin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Structure/function studies of dogfish alpha-crystallin, comparison with bovine alpha-crystallin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Some like it hot: the structure and function of small heat-shock proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Small heat shock proteins: a new classification scheme in mammals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Ser-59 is the major phosphorylation site in alphaB-crystallin accumulated in the brains of patients with Alexander's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Intermolecular exchange and stabilization of recombinant human alphaA- and alphaB-crystallin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Quaternary dynamics of αB-crystallin as a direct consequence of localised tertiary fluctuations in the C-terminus.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.318

Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.318

The small heat-shock proteins HSPB2 and HSPB3 form well-defined heterooligomers in a unique 3 to 1 subunit ratio.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.318

Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.318

A critical motif for oligomerization and chaperone activity of bacterial alpha-heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.318

The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545294

Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23188086

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wrapping the alpha-crystallin domain fold in a chaperone assembly

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23188086