GPRC5B activates obesity-associated inflammatory signaling in adipocytes (Q24304291)

protein kinase activator activity

1 reference

Fyn proto-oncogene

1 reference

G protein-coupled receptor, family C, group 5, member B

1 reference

The protein kinase IKKepsilon regulates energy balance in obese mice

1 reference

Yeon-Jeong Kim

1

Yeon-Jeong

Kim

1 reference

9 December 2023

Takamitsu Sano

2

Takamitsu

Sano

1 reference

9 December 2023

Takuji Nabetani

series ordinal

3

author given names

Takuji

author last names

Nabetani

1 reference

9 December 2023

Yoshimi Asano

series ordinal

4

author given names

Yoshimi

author last names

Asano

1 reference

9 December 2023

Yoshio Hirabayashi

series ordinal

5

author given names

Yoshio

author last names

Hirabayashi

1 reference

9 December 2023

language of work or name

English

0 references

publication date

20 November 2012

0 references

published in

Science Signaling

0 references

volume

5

0 references

issue

251

0 references

page(s)

ra85

0 references

cites work

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Comparative characterization of GPRC5B and GPRC5CLacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Caveolin is an activator of insulin receptor signaling

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003149

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Banting lecture 1988. Role of insulin resistance in human disease

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Monocyte chemoattractant protein 1 in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Fyn is required for oxidative- and hyperosmotic-stress-induced tyrosine phosphorylation of caveolin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Oxidative stress activates both Src-kinases and their negative regulator Csk and induces phosphorylation of two targeting proteins for Csk: caveolin-1 and paxillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

A Drosophila orphan G protein-coupled receptor BOSS functions as a glucose-responding receptor: loss of boss causes abnormal energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Anatomical profiling of G protein-coupled receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Induction of cell fate in the Drosophila retina: the bride of sevenless protein is predicted to contain a large extracellular domain and seven transmembrane segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Transmembrane adaptor proteins: organizers of immunoreceptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Improved method of phosphopeptides enrichment using biphasic phosphate-binding tag/C18 tip for versatile analysis of phosphorylation dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003149