The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion (Q24304143)

VPS41 subunit of HOPS complex

GOA release 2020-03-11

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late endosome to lysosome transport

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

4

Viola Oorschot

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Judith Klumperman

5

object named as

Judith Klumperman

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author name string

Maaike S Pols

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Corlinda ten Brink

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Prajakta Gosavi

Lysosomes: fusion and function

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language of work or name

English

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publication date

February 2013

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published in

Traffic

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volume

14

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issue

2

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page(s)

219-32

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cites work

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Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion

21 January 2018

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Rab conversion as a mechanism of progression from early to late endosomes

21 January 2018

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The diversity of Rab proteins in vesicle transport

21 January 2018

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Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

21 January 2018

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The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis

21 January 2018

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Vps-C complexes: gatekeepers of endolysosomal traffic

21 January 2018

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New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion

21 January 2018

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Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae

21 January 2018

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The major role of the Rab Ypt7p in vacuole fusion is supporting HOPS membrane association

21 January 2018

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The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex

21 January 2018

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hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif

21 January 2018

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Human Vam6p promotes lysosome clustering and fusion in vivo

21 January 2018

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Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization

21 January 2018

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SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery

21 January 2018

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)

21 January 2018

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Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7

21 January 2018

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Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b

21 January 2018

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Lysosomal membrane protein composition, acidic pH and sterol content are regulated via a light-dependent pathway in metazoan cells

21 January 2018

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VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease.

21 January 2018

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Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability

21 January 2018

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Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.

21 January 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

21 January 2018

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Localization of lysobisphosphatidic acid-rich membrane domains in late endosomes

21 January 2018

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VAMP-7 mediates vesicular transport from endosomes to lysosomes

21 January 2018

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Assays to assess autophagy induction and fusion of autophagic vacuoles with a degradative compartment, using monodansylcadaverine (MDC) and DQ-BSA.

21 January 2018

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New assay using fluorogenic substrates and immunofluorescence staining to measure cysteine cathepsin activity in live cell subpopulations

21 January 2018

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Lysosome and lysosome-related organelles responsible for specialized functions in higher organisms, with special emphasis on vacuolar-type proton ATPase

21 January 2018

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An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility

21 January 2018

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Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.

21 January 2018

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A dual mechanism controlling the localization and function of exocytic v-SNAREs

21 January 2018

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A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

21 January 2018

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Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line

21 January 2018

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Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis

21 January 2018

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Role of VAMP-2, VAMP-7, and VAMP-8 in constitutive exocytosis from HSY cells

21 January 2018

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Autophagosome precursor maturation requires homotypic fusion

21 January 2018

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Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes

21 January 2018

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Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion

21 January 2018

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Cryosectioning and immunolabeling

21 January 2018

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Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

21 January 2018

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Coiled-coil interactions are required for post-Golgi R-SNARE trafficking

21 January 2018

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Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling

21 January 2018

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Endosomal Fusion upon SNARE Knockdown is Maintained by Residual SNARE Activity and Enhanced Docking

21 January 2018

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Clinical and molecular genetic features of ARC syndrome

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils.

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