Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression (Q24303667)

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English	Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression	scientific article

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scholarly article

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Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression (English)

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Neuronal PAS domain protein 4

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GOA release 2020-03-11

positive regulation of transcription by RNA polymerase II

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GOA release 2020-03-11

Single-minded family bHLH transcription factor 2

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GOA release 2020-03-11

Aryl hydrocarbon receptor nuclear translocator 2

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GOA release 2020-03-11

Neuronal PAS domain protein 4

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GOA release 2020-03-11

author name string

Norihisa Ooe

1

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Koichi Saito

2

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Nobuyoshi Mikami

3

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Iwao Nakatuka

4

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Hideo Kaneko

5

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language of work or name

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publication date

January 2004

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Molecular and Cellular Biology

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24

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608-16

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2

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The murine Sim-2 gene product inhibits transcription by active repression and functional interference

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Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome

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Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development

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Physical mapping of the holoprosencephaly critical region in 21q22.3, exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of chromosome 21 important for Down syndrome

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Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

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Single-minded and Down syndrome?

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1 reference

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cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)

1 reference

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The PAS superfamily: sensors of environmental and developmental signals

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7 April 2017

Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome, a complex human obesity syndrome

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27 September 2017

Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure

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The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

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Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex.

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.".

1 reference

https://api.crossref.org/works/10.1128%2FMCB.24.2.608-616.2004

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1128/MCB.24.2.608-616.2004

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