Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy (Q24301830)

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English	Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy	scientific article

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scholarly article

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Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy (English)

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adaptive radiation therapy

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author name string

Tae Rim Kim

1

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Eun Wie Cho

2

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Sang Gi Paik

3

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In Gyu Kim

4

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language of work or name

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publication date

17 February 2012

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586

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4

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303-9

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Hypoxia and hypoxia-inducible factors: master regulators of metastasis

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Hypoxia inducible factor-1 independent pathways in tumor angiogenesis.

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Identification of new actin-associated polypeptides that are modified by viral transformation and changes in cell shape

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Fibroblast transgelin and smooth muscle SM22alpha are the same protein, the expression of which is down-regulated in many cell lines

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Ablation of SM22alpha decreases contractility and actin contents of mouse vascular smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Transgelin: an actin-binding protein and tumour suppressor

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

SM22alpha inhibits cell proliferation and protects against anticancer drugs and gamma-radiation in HepG2 cells: involvement of metallothioneins

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

SM22α-induced activation of p16INK4a/retinoblastoma pathway promotes cellular senescence caused by a subclinical dose of γ-radiation and doxorubicin in HepG2 cells

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Alpha-difluoromethylornithine, ornithine decarboxylase inhibitor, antagonizes H2O2-induced cytotoxicity in HL-60 leukemia cells: regulation of iron-dependent lysosomal damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

S-Adenosylmethionine decarboxylase partially regulates cell growth of HL-60 cells by controlling the intracellular ROS level: Early senescence and sensitization to gamma-radiation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Thioredoxin overexpression in HT-1080 cells induced cellular senescence and sensitization to gamma radiation

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors.

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Hypoxia and HIF-1alpha protect A549 cells from drug-induced apoptosis

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Insulin-like growth factor-I receptor signaling blockade combined with radiation

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Transgelin induces apoptosis of human prostate LNCaP cells through its interaction with p53.

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Proteomic analysis distinguishes basaloid carcinoma as a distinct subtype of nonsmall cell lung carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

21 January 2018

Chemotherapy resistance and oncogene expression in non-small cell lung cancer

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2011.12.036

7 January 2021

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10.1016/J.FEBSLET.2011.12.036

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