aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity (Q24301746)

establishment or maintenance of epithelial cell apical/basal polarity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Atsushi Suzuki

1

Atsushi

Suzuki

1 reference

20 April 2024

Maki Hirata

2

Maki

Hirata

1 reference

20 April 2024

Katsusi Kamimura

3

Katsusi

Kamimura

1 reference

20 April 2024

Rika Maniwa

4

Rika

Maniwa

1 reference

20 April 2024

Tomoyuki Yamanaka

5

Tomoyuki

Yamanaka

1 reference

20 April 2024

Keiko Mizuno

6

Keiko

Mizuno

1 reference

20 April 2024

Masaru Kishikawa

7

Masaru

Kishikawa

1 reference

20 April 2024

Hiroko Hirose

8

Hiroko

Hirose

1 reference

20 April 2024

Yoshiko Amano

9

Yoshiko

Amano

1 reference

20 April 2024

Natsuko Izumi

10

Natsuko

Izumi

1 reference

20 April 2024

Yoshihiro Miwa

11

Yoshihiro

Miwa

1 reference

20 April 2024

Shigeo Ohno

12

Shigeo

Construction of Epstein-Barr virus-based expression vector containing mini-oriP.

Ohno

1 reference

20 April 2024

language of work or name

English

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publication date

24 August 2004

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published in

Current Biology

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volume

14

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page(s)

1425-35

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issue

16

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cites work

1 reference

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7 January 2021

The Caenorhabditis elegans par-5 gene encodes a 14-3-3 protein required for cellular asymmetry in the early embryo

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7 January 2021

A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family.

1 reference

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7 January 2021

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.08.021

7 January 2021

Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.08.021

7 January 2021

Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity

1 reference

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7 January 2021

Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.

1 reference

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7 January 2021

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

1 reference

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7 January 2021

The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole.

1 reference

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7 January 2021

Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells

1 reference

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7 January 2021

Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.

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7 January 2021

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo

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7 January 2021

Drosophila par-1 is required for oocyte differentiation and microtubule organization.

1 reference

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7 January 2021

The fusome and microtubules enrich Par-1 in the oocyte, where it effects polarization in conjunction with Par-3, BicD, Egl, and dynein.

1 reference

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7 January 2021

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.08.021

7 January 2021

Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.08.021

7 January 2021

MAPs, MARKs and microtubule dynamics.

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7 January 2021

Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation

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7 January 2021

A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation.

1 reference

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7 January 2021

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

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7 January 2021

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

1 reference

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7 January 2021

Adaptation of core mechanisms to generate cell polarity

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7 January 2021

A genetic hierarchy controlling cell polarity.

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Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis

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7 January 2021

14-3-3 proteins; bringing new definitions to scaffolding

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14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation

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7 January 2021

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

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7 January 2021

Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactions

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7 January 2021

Microtubules are stabilized in confluent epithelial cells but not in fibroblasts

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7 January 2021

Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

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7 January 2021

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

1 reference

https://api.crossref.org/works/10.1016%2FJ.CUB.2004.08.021

7 January 2021

Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton

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7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

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7 January 2021

Morphogenesis of the polarized epithelial cell phenotype

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7 January 2021

Composition and function of PDZ protein complexes during cell polarization

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7 January 2021

Human serine/threonine protein kinase EMK1: genomic structure and cDNA cloning of isoforms produced by alternative splicing

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7 January 2021

The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium

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7 January 2021

aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization

1 reference

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7 January 2021