GPI 6150, a PARP inhibitor, reduces the colon injury caused by dinitrobenzene sulfonic acid in the rat (Q24301686)

GOA release 2020-03-11

inflammatory response

1 reference

GOA release 2020-03-11

8

Salvatore Cuzzocrea

0 references

Emanuela Mazzon

1

Emanuela Mazzon

0 references

Rosanna Di Paola

4

Rosanna Di Paola

0 references

Tiziana Genovese

5

Tiziana Genovese

0 references

Laura Dugo

2

Laura Dugo

0 references

Achille P Caputi

6

Achille P Caputi

0 references

author name string

Jia-He Li

3

0 references

Jie Zhang

Peroxynitrite-induced rat colitis--a new model of colonic inflammation

7

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language of work or name

English

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publication date

15 July 2002

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published in

Biochemical Pharmacology

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volume

64

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issue

2

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page(s)

327-37

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Increased nitric oxide synthesis in ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Oxidants and free radicals in inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Nitric oxide as a secretory product of mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Immunohistochemical demonstration of poly(adenosine diphosphate-ribose) synthetase in bovine tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Role of poly(ADP-ribose) formation in DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

DNA strand breaks, NAD metabolism, and programmed cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Beneficial effects of GPI 6150, an inhibitor of poly(ADP-ribose) polymerase in a rat model of splanchnic artery occlusion and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Inhibitors of poly(adenosine diphosphate-ribose) synthesis: effect on other metabolic processes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Active oxygen species generated by monocytes and polymorphonuclear cells in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Oxygen-derived free radical generating capacity of polymorphonuclear cells in patients with ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Mechanisms of oxidant injury of cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

GPI 6150, a poly (ADP-ribose) polymerase inhibitor, exhibits an anti-inflammatory effect in rat models of inflammation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Neutrophil-mediated tissue injury and its modulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Mediators of injury and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

The tyrosine kinase inhibitor tyrphostin AG 126 reduced the development of colitis in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Neutrophil enzyme activities in carrageenan-induced inflammation in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Multiple-organ failure and sepsis without bacteria. An experimental model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Neutrophil function and lipid peroxidation in a rat model of multiple organ failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Nicotinamide inhibits nitric oxide synthase mRNA induction in activated macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Measurement of in vivo rectal mucosal cytokine and eicosanoid production in ulcerative colitis using filter paper

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Crohn's disease is associated with novel polymorphisms in the 5'-flanking region of the tumor necrosis factor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Combination therapy of pentoxifylline and TNFalpha monoclonal antibody in dextran sulphate-induced mouse colitis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4

Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901075-4