Oligomeric peroxiredoxin-I is an essential intermediate for p53 to activate MST1 kinase and apoptosis (Q24300317)

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Y Funato

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K Uesugi

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H Miki

Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae

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language of work or name

English

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publication date

6 October 2011

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published in

Oncogene

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volume

30

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page(s)

4208-18

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issue

40

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cites work

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The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain

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Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways

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Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function

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Reactive oxygen species are downstream mediators of p53-dependent apoptosis

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Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

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The plant-specific function of 2-Cys peroxiredoxin-mediated detoxification of peroxides in the redox-hierarchy of photosynthetic electron flux

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Human peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of CYS83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2

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A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

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p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Oxidative stress-dependent structural and functional switching of a human 2-Cys peroxiredoxin isotype II that enhances HeLa cell resistance to H2O2-induced cell death.

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Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

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Mammalian sterile 20-like kinases in tumor suppression: an emerging pathway

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A model for p53-induced apoptosis

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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

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MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

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Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells

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Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

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Cell signaling. H2O2, a necessary evil for cell signaling

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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Hydrogen peroxide sensing and signaling

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A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinase

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The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

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Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

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p53 status and the efficacy of cancer therapy in vivo

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