KCNE2 protein is more abundant in ventricles than in atria and can accelerate hERG protein degradation in a phosphorylation-dependent manner (Q24300128)

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English	KCNE2 protein is more abundant in ventricles than in atria and can accelerate hERG protein degradation in a phosphorylation-dependent manner	scientific article

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scholarly article

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KCNE2 protein is more abundant in ventricles than in atria and can accelerate hERG protein degradation in a phosphorylation-dependent manner (English)

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Potassium voltage-gated channel subfamily E regulatory subunit 2

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GOA release 2020-03-11

positive regulation of proteasomal protein catabolic process

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GOA release 2020-03-11

phosphorylation

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based on heuristic

inferred from title

author name string

Mei Zhang

1

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Yuhong Wang

2

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Min Jiang

3

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Dimitar P Zankov

4

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Sabeeha Chowdhury

5

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Vigneshwar Kasirajan

6

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Gea-Ny Tseng

7

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language of work or name

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publication date

15 February 2012

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American Journal of Physiology Heart and Circulatory Physiology

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302

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4

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H910-22

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Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Probing the interaction between KCNE2 and KCNQ1 in their transmembrane regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

minK-related peptide 1 associates with Kv4.2 and modulates its gating function: potential role as beta subunit of cardiac transient outward channel?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

A minK-HERG complex regulates the cardiac potassium current I(Kr)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

MiRP1 modulates HCN2 channel expression and gating in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

KCNE2 protein is expressed in ventricles of different species, and changes in its expression contribute to electrical remodeling in diseased hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

19 March 2017

Rabs and their effectors: achieving specificity in membrane traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

7 April 2017

Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs-encoding genes and potential implications in regional heterogeneity of their expressions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

Expression of multiple KCNE genes in human heart may enable variable modulation of I(Ks).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

Cardiac IKr channels minimally comprise hERG 1a and 1b subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

27 September 2017

Mitogen-activated protein kinases control cardiac KChIP2 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322735

30 May 2018

Electrical remodeling in a canine model of ischemic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00691.2011

21 January 2018

Canine ventricular KCNE2 expression resides predominantly in Purkinje fibers.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00691.2011

21 January 2018

Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00691.2011

21 January 2018

KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00691.2011

21 January 2018

MinK-dependent internalization of the IKs potassium channel

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00691.2011

21 January 2018

Divergent expression of delayed rectifier K+ channel subunits during mouse heart development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22180649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22180649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22180649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human cardiac ion channel genes by microRNAs: theoretical perspective and pathophysiological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22180649

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00691.2011

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