Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase (Q24299772)

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Katsunori Itoh

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Hiroshi Akita

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Keiko Takano

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Satoshi Oku

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

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language of work or name

English

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publication date

9 January 2006

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published in

FEBS Letters

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volume

580

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issue

1

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page(s)

261-7

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cites work

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Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells

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Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

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NADPH oxidase activity is independent of p47phox in vitro

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Fused p47phox and p67phox truncations efficiently reconstitute NADPH oxidase with higher activity and stability than the individual components

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Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

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Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets

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Activation and assembly of the NADPH oxidase: a structural perspective

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Effects of chemotactic factors and other agents on the amounts of actin and a 65,000-mol-wt protein associated with the cytoskeleton of rabbit and human neutrophils

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Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils

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Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses

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Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase

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Inactivation of neutrophil NADPH oxidase upon dilution and its prevention by cross-link and fusion of phox proteins

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Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

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Phospholipase C-gamma 1 binds to actin-cytoskeleton via its C-terminal SH2 domain in vitro

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The NADPH oxidase components p47(phox) and p40(phox) bind to moesin through their PX domain

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p47(phox) PX domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton

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Actin enhances the activation of human neutrophil NADPH oxidase in a cell-free system

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7 January 2021

Chronic granulomatous disease

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7 January 2021

The cytosolic component p47(phox) is not a sine qua non participant in the activation of NADPH oxidase but is required for optimal superoxide production

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7 January 2021

Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivo

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7 January 2021

NAD(P)H oxidase: role in cardiovascular biology and disease

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7 January 2021