Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release (Q24299116)

E2F transcription factor 1

1 reference

RB transcriptional corepressor like 1

1 reference

E2F transcription factor 4

1 reference

Transcription factor Dp-2

1 reference

E2F transcription factor 2

1 reference

Transcription factor Dp-1

1 reference

E2F transcription factor 5

1 reference

protein domain specific binding

1 reference

Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

1 reference

Seth M Rubin

1

0 references

Anne-Laure Gall

series ordinal

2

0 references

Ning Zheng

series ordinal

3

0 references

Nikola P Pavletich

series ordinal

4

0 references

language of work or name

English

0 references

publication date

16 December 2005

0 references

published in

Cell

0 references

volume

123

0 references

page(s)

1093-106

0 references

issue

6

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

A conserved region of unknown function participates in the recognition of E2F family members by the adenovirus E4 ORF 6/7 protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The E2F transcription factor is a cellular target for the RB protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Cell cycle targets of the DNA tumor viruses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Sibling rivalry in the E2F family

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Combinatorial gene control involving E2F and E Box family members

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Transcription factor E2F binds DNA as a heterodimer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Defining the minimal portion of the retinoblastoma protein that serves as an efficient substrate for cdk4 kinase/cyclin D1 complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Identification of a growth suppression domain within the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

1 reference

7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Cumulative effect of phosphorylation of pRB on regulation of E2F activity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021

Docking-dependent regulation of the Rb tumor suppressor protein by Cdk4.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2005.09.044

7 January 2021