Subunit architecture and functional modular rearrangements of the transcriptional mediator complex (Q24298604)

Mediator complex subunit 8

1 reference

Mediator complex subunit 11

1 reference

Mediator complex subunit 30

1 reference

Mediator complex subunit 20

1 reference

Med11p YMR112C

1 reference

Mediator complex subunit SOH1 YGL127C

1 reference

Sin4p YNL236W

1 reference

Srb6p YBR253W

1 reference

Mediator complex subunit MED7 YOL135C

1 reference

Mediator complex subunit NUT2 YPR168W

1 reference

Nut1p YGL151W

1 reference

Srb4p YER022W

1 reference

Rgr1p YLR071C

1 reference

Chieri Tomomori-Sato

2

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Joan W. Conaway

object named as

Joan W Conaway

5

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author name string

Kuang-Lei Tsai

1

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Shigeo Sato

3

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Ronald C Conaway

4

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Francisco J Asturias

Human mediator subunit MED26 functions as a docking site for transcription elongation factors

6

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language of work or name

English

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publication date

5 June 2014

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published in

Cell

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volume

157

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issue

6

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page(s)

1430-44

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure of the Mediator head module

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Interaction of the Mediator Head Module with RNA Polymerase II

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Architecture of the Mediator head module

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Direct interaction of RNA polymerase II and mediator required for transcription in vivo.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure and VP16 binding of the Mediator Med25 activator interaction domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The human Mediator complex: a versatile, genome-wide regulator of transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Mediator head module structure and functional interactions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Mediator structural conservation and implications for the regulation mechanism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Identification, structure, and functional requirement of the Mediator submodule Med7N/31

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

UCSF Chimera--a visualization system for exploratory research and analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Ras induces mediator complex exchange on C/EBP beta

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure, function, and activator-induced conformations of the CRSP coactivator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Automated molecular microscopy: the new Leginon system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The Mediator complex and transcription elongation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Activator-Mediator binding regulates Mediator-cofactor interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Preparation and topology of the Mediator middle module

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

SPARX, a new environment for Cryo-EM image processing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

The structural and functional role of Med5 in the yeast Mediator tail module

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Targets of the Gal4 transcription activator in functional transcription complexes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structural organization of yeast and mammalian mediator complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Model of the Mediator middle module based on protein cross-linking.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

p53 activates transcription by directing structural shifts in Mediator

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Functional and physical interactions within the middle domain of the yeast mediator.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Structure of the mediator subunit cyclin C and its implications for CDK8 function

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Distinct conformational states of nuclear receptor-bound CRSP-Med complexes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104964

Conserved structures of mediator and RNA polymerase II holoenzyme

29 November 2018

1 reference

12 December 2020

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

1 reference

12 December 2020

The classical srb4-138 mutant allele causes dissociation of yeast Mediator

1 reference

12 December 2020

Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex.

1 reference

12 December 2020

Preparation of nuclear and cytoplasmic extracts from mammalian cells

1 reference

12 December 2020

Three-dimensional reconstruction of single particles from random and nonrandom tilt series

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

The tandem affinity purification (TAP) method: a general procedure of protein complex purification

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Appion: an integrated, database-driven pipeline to facilitate EM image processing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Iterative stable alignment and clustering of 2D transmission electron microscope images

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

PRIME: probabilistic initial 3D model generation for single-particle cryo-electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Accurate determination of local defocus and specimen tilt in electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Cryo-electron microscopy of vitrified specimens

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Plat-E: an efficient and stable system for transient packaging of retroviruses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

Preponderance of free mediator in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.05.015

7 January 2021

10.1016/J.CELL.2014.05.015

Identifiers

DOI

1 reference

566255

566255

1 reference

1 reference

1 reference