Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants (Q24298022)

heparosan-N-sulfate-glucuronate 5-epimerase activity

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Kai Li

series ordinal

1

0 references

Heather N Bethea

series ordinal

2

0 references

Jian Liu

series ordinal

3

0 references

language of work or name

English

0 references

publication date

9 April 2010

0 references

published in

0 references

volume

285

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page(s)

11106-13

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issue

15

0 references

cites work

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Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo

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Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis

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Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality

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Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling

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Characterization of the structure of antithrombin-binding heparan sulfate generated by heparan sulfate 3-O-sulfotransferase 5.

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Biosynthesis of heparin/heparan sulfate. cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung.

30 May 2018

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Generation of "neoheparin" from E. coli K5 capsular polysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.081059

The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010:K5:H4. A polymer similar to desulfo-heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.081059

Metagrowth: a new resource for the building of metabolic hypotheses in microbiology

21 January 2018

1 reference

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Biosynthesis of heparin/heparan sulfate. Purification of the D-glucuronyl C-5 epimerase from bovine liver

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20118238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heparinase II from Flavobacterium heparinum. Role of cysteine in enzymatic activity as probed by chemical modification and site- directed mutagenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20118238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.081059

0 references

Fatcat ID

release_mcixo6gos5g4razxknz3sjijn4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mcixo6gos5g4razxknz3sjijn4