Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)) (Q24294704)

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Language	Label	Description	Also known as
English	Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE))	scientific article

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scholarly article

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Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)) (English)

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Beta-secretase 1

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GOA release 2020-03-11

Phospholipid scramblase 1

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Satoshi Kametaka

1

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Masahiro Shibata

2

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Kimiho Moroe

3

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Shiro Kanamori

4

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Yoshiyuki Ohsawa

5

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Satoshi Waguri

6

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Peter J Sims

7

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Kazuo Emoto

8

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Masato Umeda

9

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Yasuo Uchiyama

10

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language of work or name

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publication date

25 April 2003

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Journal of Biological Chemistry

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278

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17

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15239-45

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

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Production of amyloid beta protein from normal amyloid beta-protein precursor (beta APP) and the mutated beta APPS linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules

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The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

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The C-terminus of the beta protein is critical in amyloidogenesis

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1 reference

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

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Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

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Cell-type and amyloid precursor protein-type specific inhibition of A beta release by bafilomycin A1, a selective inhibitor of vacuolar ATPases

1 reference

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Phosphorylation regulates intracellular trafficking of beta-secretase

1 reference

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Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain

1 reference

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

1 reference

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Functional rafts in cell membranes

1 reference

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Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

1 reference

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A detergent-insoluble membrane compartment contains A beta in vivo.

1 reference

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Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor

1 reference

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Different distribution patterns of the two mannose 6-phosphate receptors in rat liver.

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Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae

1 reference

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Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid

1 reference

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Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

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Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

1 reference

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The role of proteolysis in Alzheimer's disease

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Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery

1 reference

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Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208611200

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Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1

1 reference

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Recognition of sorting signals by clathrin adaptors

1 reference

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

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Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

1 reference

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Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein

1 reference

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Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2

1 reference

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Protein and lipid sorting from thetrans–Golgi network to the plasma membrane in polarized cells

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The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

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Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

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Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation

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Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface

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Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

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Identifiers

10.1074/JBC.M208611200

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