Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis (Q24293446)

iron-sulfur cluster assembly

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Helge Uhrigshardt

1

0 references

Anamika Singh

2

0 references

Gennadiy Kovtunovych

3

0 references

Manik Ghosh

4

0 references

Tracey A Rouault

Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease

5

0 references

language of work or name

English

0 references

publication date

1 October 2010

0 references

published in

Human Molecular Genetics

0 references

volume

19

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issue

19

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page(s)

3816-34

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cites work

1 reference

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Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly

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Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactions

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Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

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Mechanisms for regulation of Hsp70 function by Hsp40

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Identification of a novel candidate gene in the iron-sulfur pathway implicated in ataxia-susceptibility: human gene encoding HscB, a J-type co-chaperone

19 March 2017

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Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster

19 March 2017

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Characterization and description of Anaeromyxobacter dehalogenans gen. nov., sp. nov., an aryl-halorespiring facultative anaerobic myxobacterium

19 March 2017

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Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells

19 March 2017

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Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization

19 March 2017

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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

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Structure of Human J-type Co-chaperone HscB Reveals a Tetracysteine Metal-binding Domain

19 March 2017

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Crystal structure of Hsc20, a J-type Co-chaperone from Escherichia coli

19 March 2017

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Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ

19 March 2017

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

19 March 2017

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

19 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

19 March 2017

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The J-protein family: modulating protein assembly, disassembly and translocation

19 March 2017

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Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p

19 March 2017

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Ssq1, a mitochondrial Hsp70 involved in iron-sulfur (Fe/S) center biogenesis. Similarities to and differences from its bacterial counterpart

19 March 2017

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J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins

19 March 2017

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Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae

19 March 2017

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Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly

19 March 2017

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Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis

19 March 2017

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Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

19 March 2017

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RNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cells

19 March 2017

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Locating proteins in the cell using TargetP, SignalP and related tools

19 March 2017

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Structure, function, and formation of biological iron-sulfur clusters

7 April 2017

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Human ISCA1 interacts with IOP1/NARFL and functions in both cytosolic and mitochondrial iron-sulfur protein biogenesis.

7 April 2017

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The resistance of electron-transport chain Fe-S clusters to oxidative damage during the reaction of peroxynitrite with mitochondrial complex II and rat-heart pericardium

27 September 2017

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27 September 2017

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Posttranslational regulation of the scaffold for Fe-S cluster biogenesis, Isu.

27 September 2017

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27 September 2017

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The human escort protein Hep binds to the ATPase domain of mitochondrial hsp70 and regulates ATP hydrolysis

27 September 2017

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Iron-sulfur cluster biogenesis and human disease

27 September 2017

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Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases

27 September 2017

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The Hsp70 chaperone machines of Escherichia coli: a paradigm for the repartition of chaperone functions.

27 September 2017

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Molecular chaperones HscA/Ssq1 and HscB/Jac1 and their roles in iron-sulfur protein maturation

27 September 2017

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Micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes

27 September 2017

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HscA and HscB stimulate [2Fe-2S] cluster transfer from IscU to apoferredoxin in an ATP-dependent reaction

27 September 2017

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Controlled expression and functional analysis of iron-sulfur cluster biosynthetic components within Azotobacter vinelandii

27 September 2017

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The role of iron regulatory proteins in mammalian iron homeostasis and disease

27 September 2017

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Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes

27 September 2017

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Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms

27 September 2017

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27 September 2017

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Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

27 September 2017

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A specialized mitochondrial molecular chaperone system: a role in formation of Fe/S centers

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Network of protein-protein interactions among iron-sulfur cluster assembly proteins in Escherichia coli

27 September 2017

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Aconitase as Ironminus signSulfur Protein, Enzyme, and Iron-Regulatory Protein

27 September 2017

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Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae

27 September 2017

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Interaction of the iron-sulfur cluster assembly protein IscU with the Hsc66/Hsc20 molecular chaperone system of Escherichia coli

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Iron-sulfur proteins: ancient structures, still full of surprises

27 September 2017

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Structure, function and evolution of DnaJ: conservation and adaptation of chaperone function

27 September 2017

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27 September 2017

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Iron-sulfur clusters as biosensors of oxidants and iron

27 September 2017

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27 September 2017

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Kinetic characterization of the ATPase cycle of the molecular chaperone Hsc66 from Escherichia coli

30 May 2018

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30 May 2018

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Hsc66 substrate specificity is directed toward a discrete region of the iron-sulfur cluster template protein IscU.

30 May 2018

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In vitro activation of apo-aconitase using a [4Fe-4S] cluster-loaded form of the IscU [Fe-S] cluster scaffolding protein

30 May 2018

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Evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis.

29 November 2018

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Multiple turnover transfer of [2Fe2S] clusters by the iron-sulfur cluster assembly scaffold proteins IscU and IscA.

29 November 2018

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Compensation for a defective interaction of the hsp70 ssq1 with the mitochondrial Fe-S cluster scaffold isu.

29 November 2018

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A third locus for dominant optic atrophy on chromosome 22q.

29 November 2018

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Down-regulation of iron regulatory protein 1 activities and expression in superoxide dismutase 1 knock-out mice is not associated with alterations in iron metabolism

29 November 2018

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Sequence-specific interaction between mitochondrial Fe-S scaffold protein Isu and Hsp70 Ssq1 is essential for their in vivo function.

29 November 2018

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The roles of the two zinc binding sites in DnaJ.

29 November 2018

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Contributions of the LPPVK motif of the iron-sulfur template protein IscU to interactions with the Hsc66-Hsc20 chaperone system

29 November 2018

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Detection of a [3Fe-4S] cluster intermediate of cytosolic aconitase in yeast expressing iron regulatory protein 1. Insights into the mechanism of Fe-S cluster cycling

29 November 2018

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The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria

29 November 2018

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The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p

29 November 2018

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Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

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Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ301

7 January 2021