The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms (Q24293414)

apoptotic process

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Nudix (nucleoside diphosphate linked moiety X)-type motif 2

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Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] CELE_Y37H9A.6

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John B Rafferty

7

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Patrick J Baker

object named as

Patrick J Baker

5

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author name string

Scott Bailey

1

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Svetlana E Sedelnikova

2

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G Michael Blackburn

3

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Hend M Abdelghany

4

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Alexander G McLennan

Specific and nonspecific enzymes involved in the catabolism of mononucleoside and dinucleoside polyphosphates

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language of work or name

English

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publication date

April 2002

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published in

Structure

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volume

10

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issue

4

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page(s)

589-600

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cites work

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The IalA invasion gene of Bartonella bacilliformis encodes a (de)nucleoside polyphosphate hydrolase of the MutT motif family and has homologs in other invasive bacteria

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The gene, ialA, associated with the invasion of human erythrocytes by Bartonella bacilliformis, designates a nudix hydrolase active on dinucleoside 5'-polyphosphates

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Catabolism of bis(5'-nucleosidyl) oligophosphates in Escherichia coli: metal requirements and substrate specificity of homogeneous diadenosine-5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase

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The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

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A highly conserved sequence motif defining the family of MutT-related proteins from eubacteria, eukaryotes and viruses

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Cloning and expression of diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase from Lupinus angustifolius L.

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Mechanism of synthesis of adenosine(5')tetraphospho(5')adenosine (AppppA) by aminoacyl-tRNA synthetases

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Diadenosine polyphosphates: their biological and pharmacological significance.

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Diadenosine oligophosphates (Ap(n)A), a novel class of signalling molecules?

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Dinucleoside polyphosphates-friend or foe?

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Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures

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7 January 2021

Ap4A induces apoptosis in human cultured cells

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Bartonella spp. as emerging human pathogens

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Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase

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7 January 2021

The three-dimensional structure of the Nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L

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7 January 2021

The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family

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7 January 2021

Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action

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Regiospecificity of the hydrolysis of diadenosine polyphosphates catalyzed by three specific pyrophosphohydrolases.

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Identification of point of specific enzymic cleavage of P1,P4-bis(5'-adenosyl) tetraphosphate by negative ion FAB mass spectrometry

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7 January 2021

Studies on some specific Ap4A-degrading enzymes with the use of various methylene analogues of P1P4-bis-(5',5'''-adenosyl) tetraphosphate.

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7 January 2021

Recognition of beta beta'-substituted and alpha beta,alpha'beta'-disubstituted phosphonate analogues of bis(5'-adenosyl) tetraphosphate by the bis(5'-nucleosidyl)-tetraphosphate pyrophosphohydrolases from Artemia embryos and Escherichia coli

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7 January 2021

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

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7 January 2021

Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme

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7 January 2021

Metal requirements of a diadenosine pyrophosphatase from Bartonella bacilliformis: magnetic resonance and kinetic studies of the role of Mn2+.

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Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius

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The role of Glu 57 in the mechanism of the Escherichia coli MutT enzyme by mutagenesis and heteronuclear NMR.

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Structure solution by minimal-function phase refinement and Fourier filtering. II. Implementation and applications

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Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

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7 January 2021

Automated refinement of protein models

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7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

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Use of TLS parameters to model anisotropic displacements in macromolecular refinement

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PROCHECK: a program to check the stereochemical quality of protein structures

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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[31] Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

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7 January 2021