Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling (Q24292094)

1

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Lijun Wang

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Paul A B Moretti

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Nathaniel Albanese

4

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Fugui Chai

5

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Stuart M Pitson

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Richard J D'Andrea

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Jennifer R Gamble

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Mathew A Vadas

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language of work or name

English

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publication date

8 March 2002

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number of pages

8

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Journal of Biological Chemistry

inferred from page(s)

published in

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volume

277

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issue

10

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page(s)

7996-8003

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cites work

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Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

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CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase

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Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

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High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

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Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

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Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

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Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

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Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

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Functions of ceramide in coordinating cellular responses to stress

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

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7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation

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7 January 2021